FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2439879183> ?p ?o ?g. }

• W2439879183 endingPage "i110" @default.
• W2439879183 startingPage "i101" @default.
• W2439879183 abstract "Abstract Motivation: Underrepresentation of racial groups represents an important challenge and major gap in phenomics research. Most of the current human phenomics research is based primarily on European populations; hence it is an important challenge to expand it to consider other population groups. One approach is to utilize data from EMR databases that contain patient data from diverse demographics and ancestries. The implications of this racial underrepresentation of data can be profound regarding effects on the healthcare delivery and actionability. To the best of our knowledge, our work is the first attempt to perform comparative, population-scale analyses of disease networks across three different populations, namely Caucasian (EA), African American (AA) and Hispanic/Latino (HL). Results: We compared susceptibility profiles and temporal connectivity patterns for 1988 diseases and 37 282 disease pairs represented in a clinical population of 1 025 573 patients. Accordingly, we revealed appreciable differences in disease susceptibility, temporal patterns, network structure and underlying disease connections between EA, AA and HL populations. We found 2158 significantly comorbid diseases for the EA cohort, 3265 for AA and 672 for HL. We further outlined key disease pair associations unique to each population as well as categorical enrichments of these pairs. Finally, we identified 51 key ‘hub’ diseases that are the focal points in the race-centric networks and of particular clinical importance. Incorporating race-specific disease comorbidity patterns will produce a more accurate and complete picture of the disease landscape overall and could support more precise understanding of disease relationships and patient management towards improved clinical outcomes. Contacts : rong.chen@mssm.edu or joel.dudley@mssm.edu Supplementary information: Supplementary data are available at Bioinformatics online." @default.
• W2439879183 created "2016-06-24" @default.
• W2439879183 creator A5016416266 @default.
• W2439879183 creator A5019061611 @default.
• W2439879183 creator A5019610421 @default.
• W2439879183 creator A5027475930 @default.
• W2439879183 creator A5030539003 @default.
• W2439879183 creator A5032864572 @default.
• W2439879183 creator A5034893893 @default.
• W2439879183 creator A5037092893 @default.
• W2439879183 creator A5043599202 @default.
• W2439879183 creator A5046862823 @default.
• W2439879183 creator A5054839375 @default.
• W2439879183 creator A5059897389 @default.
• W2439879183 creator A5063514061 @default.
• W2439879183 creator A5071946434 @default.
• W2439879183 creator A5077594919 @default.
• W2439879183 creator A5079921592 @default.
• W2439879183 date "2016-06-11" @default.
• W2439879183 modified "2023-09-23" @default.
• W2439879183 title "Comparative analyses of population-scale phenomic data in electronic medical records reveal race-specific disease networks" @default.
• W2439879183 cites W1597690493 @default.
• W2439879183 cites W1628561756 @default.
• W2439879183 cites W1826234378 @default.
• W2439879183 cites W1839682376 @default.
• W2439879183 cites W1964716329 @default.
• W2439879183 cites W1970263201 @default.
• W2439879183 cites W1973298132 @default.
• W2439879183 cites W1974858693 @default.
• W2439879183 cites W1979421770 @default.
• W2439879183 cites W1981323832 @default.
• W2439879183 cites W1984789788 @default.
• W2439879183 cites W2004910511 @default.
• W2439879183 cites W2010707723 @default.
• W2439879183 cites W2028878367 @default.
• W2439879183 cites W2032303051 @default.
• W2439879183 cites W2041073071 @default.
• W2439879183 cites W2043570667 @default.
• W2439879183 cites W2049104279 @default.
• W2439879183 cites W2062533676 @default.
• W2439879183 cites W2068234084 @default.
• W2439879183 cites W2083045667 @default.
• W2439879183 cites W2087591041 @default.
• W2439879183 cites W2113105800 @default.
• W2439879183 cites W2115967402 @default.
• W2439879183 cites W2117281960 @default.
• W2439879183 cites W2120051475 @default.
• W2439879183 cites W2128054164 @default.
• W2439879183 cites W2138842039 @default.
• W2439879183 cites W2152415104 @default.
• W2439879183 cites W2152635811 @default.
• W2439879183 cites W2155157373 @default.
• W2439879183 cites W2157811055 @default.
• W2439879183 cites W2159092541 @default.
• W2439879183 cites W2159675211 @default.
• W2439879183 cites W2163480486 @default.
• W2439879183 cites W2165276227 @default.
• W2439879183 cites W2192798466 @default.
• W2439879183 cites W2271670697 @default.
• W2439879183 cites W2309459004 @default.
• W2439879183 cites W2313699046 @default.
• W2439879183 cites W2330428186 @default.
• W2439879183 cites W2410574058 @default.
• W2439879183 cites W2417991027 @default.
• W2439879183 cites W62210441 @default.
• W2439879183 doi "https://doi.org/10.1093/bioinformatics/btw282" @default.
• W2439879183 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4908366" @default.
• W2439879183 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27307606" @default.
• W2439879183 hasPublicationYear "2016" @default.
• W2439879183 type Work @default.
• W2439879183 sameAs 2439879183 @default.
• W2439879183 citedByCount "38" @default.
• W2439879183 countsByYear W24398791832016 @default.
• W2439879183 countsByYear W24398791832017 @default.
• W2439879183 countsByYear W24398791832018 @default.
• W2439879183 countsByYear W24398791832019 @default.
• W2439879183 countsByYear W24398791832020 @default.
• W2439879183 countsByYear W24398791832021 @default.
• W2439879183 countsByYear W24398791832022 @default.
• W2439879183 countsByYear W24398791832023 @default.
• W2439879183 crossrefType "journal-article" @default.
• W2439879183 hasAuthorship W2439879183A5016416266 @default.
• W2439879183 hasAuthorship W2439879183A5019061611 @default.
• W2439879183 hasAuthorship W2439879183A5019610421 @default.
• W2439879183 hasAuthorship W2439879183A5027475930 @default.
• W2439879183 hasAuthorship W2439879183A5030539003 @default.
• W2439879183 hasAuthorship W2439879183A5032864572 @default.
• W2439879183 hasAuthorship W2439879183A5034893893 @default.
• W2439879183 hasAuthorship W2439879183A5037092893 @default.
• W2439879183 hasAuthorship W2439879183A5043599202 @default.
• W2439879183 hasAuthorship W2439879183A5046862823 @default.
• W2439879183 hasAuthorship W2439879183A5054839375 @default.
• W2439879183 hasAuthorship W2439879183A5059897389 @default.
• W2439879183 hasAuthorship W2439879183A5063514061 @default.
• W2439879183 hasAuthorship W2439879183A5071946434 @default.
• W2439879183 hasAuthorship W2439879183A5077594919 @default.
• W2439879183 hasAuthorship W2439879183A5079921592 @default.
• W2439879183 hasBestOaLocation W24398791831 @default.

• next