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- W2440185819 abstract "The correlation between serum concentration of methoxsalen (8-methoxypsoralen; 8-MOP) and phototoxic effect using long-wave ultraviolet light has been studied in 5 psoriatic patients. The maximum serum concentration occurred between 0.5 and 2 hr after oral administration of 0.6 mg/kg of methoxsalen. The lowest value for the minimum phototoxic dose (MPD), i.e., highest photosensitivity, was obtained between 1 and 2 hr. There was a significant negative correlation between the logarithm of the serum concentration and minimum phototoxic dose (MPD) (r = 0.780). Hence, the degree of photosensitivity appears to be related to the serum level of methoxsalen." @default.
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- W2440185819 date "1979-04-01" @default.
- W2440185819 modified "2023-10-17" @default.
- W2440185819 title "Serum concentration and phototoxic effect of methoxsalen in patients with psoriasis" @default.
- W2440185819 doi "https://doi.org/10.1002/cpt1979254478" @default.
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