Matches in SemOpenAlex for { <https://semopenalex.org/work/W2440703637> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W2440703637 endingPage "8" @default.
- W2440703637 startingPage "46" @default.
- W2440703637 abstract "The antiarrhythmic and local anesthetic effects of 4 metabolites (G 491, ABD 19-200, ABD 19-199, ABD 19-205) of a new antiarrhythmic drug bonnecor (GS-015) were studied on the models of arrhythmias induced by aconitine (rats), barium chloride (rabbits), electrical fibrillation (cats), ouabain (dogs) as well as surface anesthesia (rabbit cornea). The side effects on the cardiovascular system were investigated on anesthetized cats. As compared with the original compound (bonnecor) metabolites G 491 and ABD 19-200 on different test models exhibited the action which on the antiarrhythmic terms was 2-14 times less weak than that of bonnecor but the metabolites were less toxic. Metabolites ABD 19-199 and ABD 19-205 reach the degree of effectiveness of bonnecor but their toxicity is higher. It follows from the above that the beneficial effect of bonnecor is not achieved by its metabolites." @default.
- W2440703637 created "2016-06-24" @default.
- W2440703637 creator A5066296239 @default.
- W2440703637 creator A5073945687 @default.
- W2440703637 date "1990-05-01" @default.
- W2440703637 modified "2023-09-25" @default.
- W2440703637 title "[Pharmacological research on bonnecor and its metabolites]." @default.
- W2440703637 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2387381" @default.
- W2440703637 hasPublicationYear "1990" @default.
- W2440703637 type Work @default.
- W2440703637 sameAs 2440703637 @default.
- W2440703637 citedByCount "0" @default.
- W2440703637 crossrefType "journal-article" @default.
- W2440703637 hasAuthorship W2440703637A5066296239 @default.
- W2440703637 hasAuthorship W2440703637A5073945687 @default.
- W2440703637 hasConcept C126322002 @default.
- W2440703637 hasConcept C178790620 @default.
- W2440703637 hasConcept C185592680 @default.
- W2440703637 hasConcept C2777477808 @default.
- W2440703637 hasConcept C2777547430 @default.
- W2440703637 hasConcept C2778162923 @default.
- W2440703637 hasConcept C2779133857 @default.
- W2440703637 hasConcept C2779904517 @default.
- W2440703637 hasConcept C2780035454 @default.
- W2440703637 hasConcept C2781005686 @default.
- W2440703637 hasConcept C42219234 @default.
- W2440703637 hasConcept C537181965 @default.
- W2440703637 hasConcept C55493867 @default.
- W2440703637 hasConcept C71924100 @default.
- W2440703637 hasConcept C98274493 @default.
- W2440703637 hasConceptScore W2440703637C126322002 @default.
- W2440703637 hasConceptScore W2440703637C178790620 @default.
- W2440703637 hasConceptScore W2440703637C185592680 @default.
- W2440703637 hasConceptScore W2440703637C2777477808 @default.
- W2440703637 hasConceptScore W2440703637C2777547430 @default.
- W2440703637 hasConceptScore W2440703637C2778162923 @default.
- W2440703637 hasConceptScore W2440703637C2779133857 @default.
- W2440703637 hasConceptScore W2440703637C2779904517 @default.
- W2440703637 hasConceptScore W2440703637C2780035454 @default.
- W2440703637 hasConceptScore W2440703637C2781005686 @default.
- W2440703637 hasConceptScore W2440703637C42219234 @default.
- W2440703637 hasConceptScore W2440703637C537181965 @default.
- W2440703637 hasConceptScore W2440703637C55493867 @default.
- W2440703637 hasConceptScore W2440703637C71924100 @default.
- W2440703637 hasConceptScore W2440703637C98274493 @default.
- W2440703637 hasIssue "3" @default.
- W2440703637 hasLocation W24407036371 @default.
- W2440703637 hasOpenAccess W2440703637 @default.
- W2440703637 hasPrimaryLocation W24407036371 @default.
- W2440703637 hasRelatedWork W1981952713 @default.
- W2440703637 hasRelatedWork W2141845144 @default.
- W2440703637 hasRelatedWork W2361501659 @default.
- W2440703637 hasRelatedWork W2362092210 @default.
- W2440703637 hasRelatedWork W2367309295 @default.
- W2440703637 hasRelatedWork W2386242562 @default.
- W2440703637 hasRelatedWork W2410578592 @default.
- W2440703637 hasRelatedWork W2440703637 @default.
- W2440703637 hasRelatedWork W2464553039 @default.
- W2440703637 hasRelatedWork W2899084033 @default.
- W2440703637 hasVolume "53" @default.
- W2440703637 isParatext "false" @default.
- W2440703637 isRetracted "false" @default.
- W2440703637 magId "2440703637" @default.
- W2440703637 workType "article" @default.