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- W2441320123 abstract "When a strain of Saccharomyces cerevisiae monosomic for chromosome I and initially deficient for 25% of the genes coding for ribosomal RNA is repeatedly subcult- ured, the number of these genes increases to and remains stable at the number in the wild type. This strain shows 2:2; viable: inviable first division segregation and hemizygosity for the adel gene (a chromosome I marker), evidence that the strain is still monosomic for chromosome I. The increase in the number of genes coding for ribosomal RNA in yeast may be analogous to the magnification of the ribosomal RNA genes in Drosophila melanogaster bobbed mutants. Saccharomyces cerevisiae contains approximately 140 genes coding for rRNA per haploid genome (1). Approximately 60% of these genes are located on chromosome I (2-4) while the remainder are thought to be located on at least one but not more than two other chromosomes (5). The number of rRNA genes had appeared to be invarient because several unirelated euploid strains contain the same number of rRNA genes (1, 2, 4). Re- cently, a strain with an unusually high proportion of DNA coding for rRNA (rDNA) has been found (6); however, the nature of this increase has not been investigated." @default.
- W2441320123 created "2016-06-24" @default.
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- W2441320123 date "2016-01-01" @default.
- W2441320123 modified "2023-09-27" @default.
- W2441320123 title "Magnification of genes coding for ribosomal RNA in Saccharomyces" @default.
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