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- W2441437540 abstract "Osteoporosis is a complex multifactorial condition characterized by progressive loss of bone mass and microarchitectural deterioration, leading to increased bone fragility and susceptibility to fractures [1]. Although it occurs most commonly in the elderly (women and men alike) as a result of sex hormone deficiency (primary, involutional osteoporosis), it is increasingly recognized that osteoporosis also affects other high risk pediatric and adult populations (secondary osteoporosis). Bone development during childhood and adolescence is a key determinant of adult skeleton health. A reduced bone mass is associated with increased fracture risk in adults as well as in children. Peak bone mass, which is reached by early adulthood, serves as a bone reserve for the remainder of life, therefore childhood and adolescence are crucial periods for bone development. Strategies implemented for optimization of bone acquisition, as well as factors adversely affecting bone growth during these susceptible periods can have potentially long-standing consequences." @default.
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- W2441437540 date "2003-07-01" @default.
- W2441437540 modified "2023-10-17" @default.
- W2441437540 title "Osteoporosis in pediatrics." @default.
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