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- W2441630863 abstract "The effects of the environment, particularly dietary factors, may influence in the development and prevention of cancer. Vitamin D (colecalciferol) has been associated for years with calcium homeostasis regulation, but many epidemiological, biochemical and genetic studies reveal non classic effects of vitamin D, such as vitamin D involvement in the progression of different types of cancer. The aim of the present article was to give a review about the molecular mechanisms of the antineoplasic action of vitamin D. These effects are still not completely established, but it is well known that vitamin D induces cellular arrest, triggers apoptotic pathways, inhibits angiogenesis and alters cellular adhesion. To maintain suitable vitamin D levels seems to be necessary for many physiological processes, and not only for bone homeostasis. Clinical studies might determine vitamin D levels that can also protect against the cancer development." @default.
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- W2441630863 date "2008-01-01" @default.
- W2441630863 modified "2023-09-23" @default.
- W2441630863 title "[Molecular aspects of antineoplasic action of vitamin D]." @default.
- W2441630863 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20803935" @default.
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