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- W2441736802 abstract "Neonatal alloimmune thrombocytopenia (NAIT) is caused by maternal immunization against fetal platelet antigens. In the serum of a mother who gave birth to a child with the typical clinical picture of NAIT we found an antibody directed against the new platelet antigen Sra. Anti-Sra was found to react in the immunofluorescence test and in a glycoprotein (GP) specific immunoassay (MAIPA) using a monoclonal antibody against GP IIb/IIIa for antigen immobilization with the child's and father's platelets. Radioimmunoprecipitation and immunoblot allowed to assign the Sra-antigen to GP IIIa. The phenotype frequency was estimated less than 1%, characterising the Sra-antigen as the first 'private' alloantigen on platelets." @default.
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- W2441736802 date "1990-01-01" @default.
- W2441736802 modified "2023-09-23" @default.
- W2441736802 title "[Sr(a), a private thrombocyte alloantigen as a cause of neonatal alloimmune thrombocytopenia]." @default.
- W2441736802 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1703881" @default.
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