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- W2442052008 abstract "Cleavage by restriction endonucleases MvaI kappa EcoRII of DNA duplexes, in which the internal deoxycytidine in one of the strands of the recognition site is substituted for 5-fluorodeoxycytidine, has been studied. It has been found that the modified strands of these duplexes are scissed by endonuclease MvaI with a greater efficiency than the intact ones. Endonuclease EcoRII does not practically cleave such substrate analogs. The UV absorbance spectra of 5-fluorodeoxycytidine and the 14-member oligodeoxyribonucleotide with modification in the middle of the strand have been measured. A hypothesis has been put forward about the structural features of 5-fluorodeoxycytidine-containing DNA duplexes." @default.
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- W2442052008 date "1993-11-01" @default.
- W2442052008 modified "2023-09-23" @default.
- W2442052008 title "[Hydrolysis of DNA-duplexes, containing 5-fluorodeoxycytidine by restriction endonucleases]." @default.
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