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• W2442293169 endingPage "59" @default.
• W2442293169 startingPage "59" @default.
• W2442293169 abstract "Pancreatic ductal adenocarcinoma (PDAC) remains a very challenging malignancy. Disease is diagnosed in an advanced stage in the vast majority of patients, and PDAC cells are often resistant to conventional cytotoxic drugs. Targeted therapies have made no progress in the management of this disease, unlike other cancers. microRNAs (miRs) are small non-coding RNAs that regulate the expression of multitude number of genes by targeting their 3′-UTR mRNA region. Aberrant expression of miRNAs has been linked to the development of various malignancies, including PDAC. In PDAC, a series of miRs have been defined as holding promise for early diagnostics, as indicators of therapy resistance, and even as markers for therapeutic response in patients. In this mini-review, we present an update on the various different miRs that have been defined in PDAC biology." @default.
• W2442293169 created "2016-06-24" @default.
• W2442293169 creator A5011312785 @default.
• W2442293169 creator A5011817630 @default.
• W2442293169 creator A5056962753 @default.
• W2442293169 creator A5078114527 @default.
• W2442293169 creator A5085875893 @default.
• W2442293169 date "2016-06-16" @default.
• W2442293169 modified "2023-09-27" @default.
• W2442293169 title "The Role of microRNAs in the Diagnosis and Treatment of Pancreatic Adenocarcinoma" @default.
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