Matches in SemOpenAlex for { <https://semopenalex.org/work/W2443059106> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2443059106 endingPage "9" @default.
- W2443059106 startingPage "177" @default.
- W2443059106 abstract "To determine whether fibroblasts can be used to promote endochondral bone formation in vivo by transfer of human bone morphogenetic protein-2(hBMP-2) into fibroblasts.pcDNA3-hBMP-2 was constructed by use of gene clone and recombined technique. NIH3T3 fibroblasts were transfected with pcDNA3-hBMP-2. The positive cell clones were selected with G418. In NIH3T3 fibroblasts transferred with pcDNA3-hBMP-2, the expression of hBMP-2 was determined by in situ hybridization and immunohistochemical analysis; alkaline phosphatase activity was measured. hBMP-2-producing fibroblasts were implanted into nude mouse muscle to observe endochondral bone formation in vivo.pcDNA3-hBMP-2 was successfully constructed. In NIH3T3 fibroblasts transfected with pcDNA3-hBMP-2, the BMP-2 expression was stable; alkaline phophatase activity was much higher than that in non-transfected NIH3T3 cells. Endochondral bone formation in vivo was observed at the site of implantation 4 weeks later.Fibroblasts transfected by hBMP-2 gene can be used to promote endochondral bone formation in vivo." @default.
- W2443059106 created "2016-06-24" @default.
- W2443059106 creator A5061390923 @default.
- W2443059106 creator A5078313835 @default.
- W2443059106 date "2003-05-01" @default.
- W2443059106 modified "2023-10-18" @default.
- W2443059106 title "[In vivo endochondral bone formation by implanting human bone morphogenetic protein-2-producing fibroblasts into nude mouse muscle]." @default.
- W2443059106 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12822343" @default.
- W2443059106 hasPublicationYear "2003" @default.
- W2443059106 type Work @default.
- W2443059106 sameAs 2443059106 @default.
- W2443059106 citedByCount "0" @default.
- W2443059106 crossrefType "journal-article" @default.
- W2443059106 hasAuthorship W2443059106A5061390923 @default.
- W2443059106 hasAuthorship W2443059106A5078313835 @default.
- W2443059106 hasConcept C104317684 @default.
- W2443059106 hasConcept C105702510 @default.
- W2443059106 hasConcept C125349252 @default.
- W2443059106 hasConcept C150903083 @default.
- W2443059106 hasConcept C153911025 @default.
- W2443059106 hasConcept C160160445 @default.
- W2443059106 hasConcept C17938293 @default.
- W2443059106 hasConcept C181199279 @default.
- W2443059106 hasConcept C181628713 @default.
- W2443059106 hasConcept C185592680 @default.
- W2443059106 hasConcept C202751555 @default.
- W2443059106 hasConcept C207001950 @default.
- W2443059106 hasConcept C2780550940 @default.
- W2443059106 hasConcept C30352789 @default.
- W2443059106 hasConcept C31507581 @default.
- W2443059106 hasConcept C54009773 @default.
- W2443059106 hasConcept C55493867 @default.
- W2443059106 hasConcept C86803240 @default.
- W2443059106 hasConcept C95444343 @default.
- W2443059106 hasConceptScore W2443059106C104317684 @default.
- W2443059106 hasConceptScore W2443059106C105702510 @default.
- W2443059106 hasConceptScore W2443059106C125349252 @default.
- W2443059106 hasConceptScore W2443059106C150903083 @default.
- W2443059106 hasConceptScore W2443059106C153911025 @default.
- W2443059106 hasConceptScore W2443059106C160160445 @default.
- W2443059106 hasConceptScore W2443059106C17938293 @default.
- W2443059106 hasConceptScore W2443059106C181199279 @default.
- W2443059106 hasConceptScore W2443059106C181628713 @default.
- W2443059106 hasConceptScore W2443059106C185592680 @default.
- W2443059106 hasConceptScore W2443059106C202751555 @default.
- W2443059106 hasConceptScore W2443059106C207001950 @default.
- W2443059106 hasConceptScore W2443059106C2780550940 @default.
- W2443059106 hasConceptScore W2443059106C30352789 @default.
- W2443059106 hasConceptScore W2443059106C31507581 @default.
- W2443059106 hasConceptScore W2443059106C54009773 @default.
- W2443059106 hasConceptScore W2443059106C55493867 @default.
- W2443059106 hasConceptScore W2443059106C86803240 @default.
- W2443059106 hasConceptScore W2443059106C95444343 @default.
- W2443059106 hasIssue "3" @default.
- W2443059106 hasLocation W24430591061 @default.
- W2443059106 hasOpenAccess W2443059106 @default.
- W2443059106 hasPrimaryLocation W24430591061 @default.
- W2443059106 hasRelatedWork W1946117573 @default.
- W2443059106 hasRelatedWork W2058276650 @default.
- W2443059106 hasRelatedWork W2092289200 @default.
- W2443059106 hasRelatedWork W2108879229 @default.
- W2443059106 hasRelatedWork W21838000 @default.
- W2443059106 hasRelatedWork W2378162109 @default.
- W2443059106 hasRelatedWork W2392181836 @default.
- W2443059106 hasRelatedWork W2443059106 @default.
- W2443059106 hasRelatedWork W3031612862 @default.
- W2443059106 hasRelatedWork W3143368602 @default.
- W2443059106 hasVolume "17" @default.
- W2443059106 isParatext "false" @default.
- W2443059106 isRetracted "false" @default.
- W2443059106 magId "2443059106" @default.
- W2443059106 workType "article" @default.