Matches in SemOpenAlex for { <https://semopenalex.org/work/W2443156633> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W2443156633 endingPage "6" @default.
- W2443156633 startingPage "43" @default.
- W2443156633 abstract "Weekly docetaxel therapy is a new therapeutical form of relapsed ovarian cancer. Phase I and II trials of this administration form are rare in the literature of this tumor type. The authors report on a retrospective study of this treatment.Ten patients with recurrent epithelial ovarian carcinoma were treated by dose-dense weekly docetaxel in 57 courses. The patients received a median of 6 courses of docetaxel on day 1, 8 and 15 together with a one-week pause, in 4-week courses. The average age of the patients was 61+/-9 years. Eight patients received a docetaxel monotherapy at a dose of 40 mg/m2, in weekly administration, and two patients weekly docetaxel combination therapy with carboplatin of AUC 3, on the same days as above. The premedication used before docetaxel was the same as the one given in the 3-week protocols: the patients received treatments of 100 mg methyl-prednisolone 12 hours and half an hour before docetaxel infusion. No G4 hematological toxicities were observed. G3 and G2 leucopenia was found in 6/57=11% and 4/57=8% of treatments. No granulocyte colony stimulating factor was given. Progression-free interval (PFI) was calculated by GraphPad Prism (version 2.0) program.Complete response was found in two patients (2/10=20%), and the patients are tumor-free 2 and 3 months after treatment. All the other patients showed tumor progression after some time of stabilization. The median progression-free interval was calculated as 2 months.Weekly docetaxel is found to be a tolerable treatment form of relapsed ovarian cancer patients. For the evaluation of the treatment more studies are warranted." @default.
- W2443156633 created "2016-06-24" @default.
- W2443156633 creator A5000578734 @default.
- W2443156633 creator A5091246547 @default.
- W2443156633 date "2006-01-01" @default.
- W2443156633 modified "2023-09-23" @default.
- W2443156633 title "[First observations of the dose-dense weekly docetaxel therapy in relapsed ovarian cancer]." @default.
- W2443156633 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16617383" @default.
- W2443156633 hasPublicationYear "2006" @default.
- W2443156633 type Work @default.
- W2443156633 sameAs 2443156633 @default.
- W2443156633 citedByCount "0" @default.
- W2443156633 crossrefType "journal-article" @default.
- W2443156633 hasAuthorship W2443156633A5000578734 @default.
- W2443156633 hasAuthorship W2443156633A5091246547 @default.
- W2443156633 hasConcept C121608353 @default.
- W2443156633 hasConcept C126322002 @default.
- W2443156633 hasConcept C141071460 @default.
- W2443156633 hasConcept C143998085 @default.
- W2443156633 hasConcept C2776694085 @default.
- W2443156633 hasConcept C2776715498 @default.
- W2443156633 hasConcept C2778239845 @default.
- W2443156633 hasConcept C2778300832 @default.
- W2443156633 hasConcept C2780427987 @default.
- W2443156633 hasConcept C2781190966 @default.
- W2443156633 hasConcept C2781451048 @default.
- W2443156633 hasConcept C71924100 @default.
- W2443156633 hasConcept C90924648 @default.
- W2443156633 hasConceptScore W2443156633C121608353 @default.
- W2443156633 hasConceptScore W2443156633C126322002 @default.
- W2443156633 hasConceptScore W2443156633C141071460 @default.
- W2443156633 hasConceptScore W2443156633C143998085 @default.
- W2443156633 hasConceptScore W2443156633C2776694085 @default.
- W2443156633 hasConceptScore W2443156633C2776715498 @default.
- W2443156633 hasConceptScore W2443156633C2778239845 @default.
- W2443156633 hasConceptScore W2443156633C2778300832 @default.
- W2443156633 hasConceptScore W2443156633C2780427987 @default.
- W2443156633 hasConceptScore W2443156633C2781190966 @default.
- W2443156633 hasConceptScore W2443156633C2781451048 @default.
- W2443156633 hasConceptScore W2443156633C71924100 @default.
- W2443156633 hasConceptScore W2443156633C90924648 @default.
- W2443156633 hasIssue "1" @default.
- W2443156633 hasLocation W24431566331 @default.
- W2443156633 hasOpenAccess W2443156633 @default.
- W2443156633 hasPrimaryLocation W24431566331 @default.
- W2443156633 hasRelatedWork W2017764465 @default.
- W2443156633 hasRelatedWork W2024074772 @default.
- W2443156633 hasRelatedWork W2049333033 @default.
- W2443156633 hasRelatedWork W2056584284 @default.
- W2443156633 hasRelatedWork W2070750638 @default.
- W2443156633 hasRelatedWork W2099215460 @default.
- W2443156633 hasRelatedWork W2125904513 @default.
- W2443156633 hasRelatedWork W2130747549 @default.
- W2443156633 hasRelatedWork W2131964390 @default.
- W2443156633 hasRelatedWork W2201320088 @default.
- W2443156633 hasRelatedWork W2274999288 @default.
- W2443156633 hasRelatedWork W2350245541 @default.
- W2443156633 hasRelatedWork W2353663633 @default.
- W2443156633 hasRelatedWork W2354263381 @default.
- W2443156633 hasRelatedWork W2386320079 @default.
- W2443156633 hasRelatedWork W2390333244 @default.
- W2443156633 hasRelatedWork W2602503472 @default.
- W2443156633 hasRelatedWork W2898193240 @default.
- W2443156633 hasRelatedWork W2996211065 @default.
- W2443156633 hasRelatedWork W3137999899 @default.
- W2443156633 hasVolume "50" @default.
- W2443156633 isParatext "false" @default.
- W2443156633 isRetracted "false" @default.
- W2443156633 magId "2443156633" @default.
- W2443156633 workType "article" @default.