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• W2443220025 abstract "Gastric cancer is one of the most commonplace and lethal cancers in the world. Molecular investigation of this disease, in order to obtain diagnostic and treatments achievements is important and vital. Relatively, in this research study, one of the most important epigenetic factors, the methylation of CDX2 gene was investigated in tumoral and non-tumoral tissues of gastric cancer patients by bisulfite treatment followed by sequencing of the 5'UTR region of CDX2 in both tissues. The results indicated a hypomethylation in tumoral tissues of adenocarcinoma. Consequently, the methylation amount of CDX2 in tumoral tissues was significantly reduced compared with non-tumoral tissues." @default.
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• W2443220025 date "2016-05-02" @default.
• W2443220025 modified "2023-10-18" @default.
• W2443220025 title "Epigenetic changes of CDX2 in gastric adenocarcinoma" @default.
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• W2443220025 doi "https://doi.org/10.1007/s12079-016-0327-9" @default.
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