Matches in SemOpenAlex for { <https://semopenalex.org/work/W2443246688> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W2443246688 endingPage "7" @default.
- W2443246688 startingPage "395" @default.
- W2443246688 abstract "To investigate the effects of alcohol and high-fat diet on the expression of PI-3K-P85alpha in rat adipose tissue, and in order to explore the effects on insulin sensitivity and the molecular mechanisms induced by combination of alcohol and high-fat diet.The rats were treated by alcohol and high-fat. Then the contents of fasting plasma glucose and insulin, and HOMA-IR index of each group were calculated. Expression of PI-3K-P85alpha were detectedby RT-PCR and Western blotting.In comparison with normal diet group, HOMA-IR index of high-fat groups increased, in comparison with high-fat control group, the contents of fasting plasma glucose increased in alcohol combined with high-fat groups, and HOMA-IR increased both in the low-dose and middle-dose alcohol combined with high-fat model groups. Expressions of PI-3K-P85alpha remarkably decreased in all the alcohol and high-fat model groups (P < 0.05).High-fat diet could induce insulin resistance. Compared with high-fat diet alone, alcohol combined with high-fat could aggravate insulin resistance. The changes of PI-3K-P85alpha expression in adipose tissue may be one of the molecular mechanism of insulin resistance induced by alcohol combined high-fat diet." @default.
- W2443246688 created "2016-06-24" @default.
- W2443246688 creator A5004970256 @default.
- W2443246688 creator A5019763295 @default.
- W2443246688 creator A5045843728 @default.
- W2443246688 creator A5087235746 @default.
- W2443246688 date "2009-07-01" @default.
- W2443246688 modified "2023-09-27" @default.
- W2443246688 title "[Effects of alcohol and high-fat diet on the expression of phosphatidylinositol 3-kinase in rat adipose tissue]." @default.
- W2443246688 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19689064" @default.
- W2443246688 hasPublicationYear "2009" @default.
- W2443246688 type Work @default.
- W2443246688 sameAs 2443246688 @default.
- W2443246688 citedByCount "0" @default.
- W2443246688 crossrefType "journal-article" @default.
- W2443246688 hasAuthorship W2443246688A5004970256 @default.
- W2443246688 hasAuthorship W2443246688A5019763295 @default.
- W2443246688 hasAuthorship W2443246688A5045843728 @default.
- W2443246688 hasAuthorship W2443246688A5087235746 @default.
- W2443246688 hasConcept C112446052 @default.
- W2443246688 hasConcept C126322002 @default.
- W2443246688 hasConcept C134018914 @default.
- W2443246688 hasConcept C171089720 @default.
- W2443246688 hasConcept C185592680 @default.
- W2443246688 hasConcept C2776175234 @default.
- W2443246688 hasConcept C2777391703 @default.
- W2443246688 hasConcept C2779306644 @default.
- W2443246688 hasConcept C2781066024 @default.
- W2443246688 hasConcept C55493867 @default.
- W2443246688 hasConcept C71924100 @default.
- W2443246688 hasConcept C86803240 @default.
- W2443246688 hasConceptScore W2443246688C112446052 @default.
- W2443246688 hasConceptScore W2443246688C126322002 @default.
- W2443246688 hasConceptScore W2443246688C134018914 @default.
- W2443246688 hasConceptScore W2443246688C171089720 @default.
- W2443246688 hasConceptScore W2443246688C185592680 @default.
- W2443246688 hasConceptScore W2443246688C2776175234 @default.
- W2443246688 hasConceptScore W2443246688C2777391703 @default.
- W2443246688 hasConceptScore W2443246688C2779306644 @default.
- W2443246688 hasConceptScore W2443246688C2781066024 @default.
- W2443246688 hasConceptScore W2443246688C55493867 @default.
- W2443246688 hasConceptScore W2443246688C71924100 @default.
- W2443246688 hasConceptScore W2443246688C86803240 @default.
- W2443246688 hasIssue "4" @default.
- W2443246688 hasLocation W24432466881 @default.
- W2443246688 hasOpenAccess W2443246688 @default.
- W2443246688 hasPrimaryLocation W24432466881 @default.
- W2443246688 hasRelatedWork W1984913861 @default.
- W2443246688 hasRelatedWork W1985816784 @default.
- W2443246688 hasRelatedWork W2017606817 @default.
- W2443246688 hasRelatedWork W2037142192 @default.
- W2443246688 hasRelatedWork W2058304021 @default.
- W2443246688 hasRelatedWork W2069380359 @default.
- W2443246688 hasRelatedWork W2123350325 @default.
- W2443246688 hasRelatedWork W2172026176 @default.
- W2443246688 hasRelatedWork W2294040377 @default.
- W2443246688 hasRelatedWork W2412622551 @default.
- W2443246688 hasVolume "38" @default.
- W2443246688 isParatext "false" @default.
- W2443246688 isRetracted "false" @default.
- W2443246688 magId "2443246688" @default.
- W2443246688 workType "article" @default.