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- W2444655178 abstract "Objective To study the effects of hydrogen peroxide on human mitochondrial gene expression of intestinal epithelial cells by using in vitro model of hydrogen peroxide stimulated SW 480 cell line.Methods Human intestinal epithelial cell were treated with 400 μmol/L and 400 mmol/L hydrogen peroxide and RNA of hydrogen peroxide induced SW 480 cell line was isolated. Changes in ATPase 6, ATPase 8, COI,COII and COIII gene expressions were studied through reverse transcriptional polymerase chain reaction(RT PCR).Results Hydrogen peroxide induced significant changes in mitochondrial gene expression,but the changes were not in consistence with changes in dosage of hydrogen peroxide.Conclusion Differential expressions of mithochondrial gene may be one of the mechanisms involved in hydrogen peroxide induced apoptosis of human intestinal epithelial cells." @default.
- W2444655178 created "2016-06-24" @default.
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- W2444655178 date "2002-01-01" @default.
- W2444655178 modified "2023-09-23" @default.
- W2444655178 title "Effects of hydrogen peroxide on human mitochondrial gene expression of intestinal epithelial cells" @default.
- W2444655178 hasPublicationYear "2002" @default.
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