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- W2460176552 abstract "1-Alk-1'-enyl-2-acyl-sn-glycero-3-phosphoethanolamine (plasmenylethanolamine) is a significant phospholipid component of many mammalian tissues. Plasmenylethanolamine contains relatively high concentrations of polyunsaturated fatty acids; and this phospholipid subclass has been proposed as a storage site and source of arachidonic acid. It has also been suggested that ethanolamine plasmalogens function as scavengers of oxidative free radicals in biological membranes. Plasmanylethanolamine desaturase is a membrane-bound enzyme that converts plasmanylethanolamine (1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine) to plasmenylethanolamine via an electron transport chain involving cytochrome b5, molecular oxygen, and either NADPH or NADH as cofactors. Tissues and cells used as enzyme sources to study plasmanylethanolamine desaturase include Ehrlich ascites cells, Fischer R-3259 sarcomas, rat brains, preputial gland tumors, Madin-Darby canine kidney cells, P388D1 cells, and hamster small intestines. The plasmanylethanolamine desaturase resides in the microsomal membrane fraction, although postmitochondrial supernatant fractions have also been used in some Δ1-desaturase studies." @default.
- W2460176552 created "2016-07-22" @default.
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- W2460176552 date "1992-01-01" @default.
- W2460176552 modified "2023-09-30" @default.
- W2460176552 title "[46] Plasmanylethanolamine Δ1-desaturase" @default.
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- W2460176552 doi "https://doi.org/10.1016/0076-6879(92)09048-8" @default.
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