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- W2460469759 abstract "Les évolutions technologiques récentes ont permis de développer le concept de « radiothérapie hépatique focalisée ». Il convient de distinguer les tumeurs primitives de celles secondaires car les indications sont restreintes et doivent être discutées en alternative aux traitements chirurgicaux ou médicaux. Dans ce cas, pour les carcinomes hépatocellulaires de 5 à 10 cm (voire plus), une irradiation conformationnelle avec ou sans modulation d’intensité est réalisée. La radiothérapie en conditions stéréotaxiques est en cours d’évaluation et est souvent préférée à la radiofréquence pour les tumeurs primitives ou secondaires (en général de moins de 5 cm). Les mouvements de la tumeur (et du foie) liés à la respiration doivent être pris en compte. Il faut respecter des critères dosimétriques stricts avec une attention toute particulière sur les histogrammes dose–volume (HDV) du foie non tumoral ainsi que des organes creux, notamment en cas de radiothérapie en conditions stéréotaxiques. Recent technological developments led to develop the concept of focused liver radiation therapy. We must distinguish primary and secondary tumors as the indications are restricted and must be discussed as an alternative to surgical or medical treatments. For hepatocellular carcinoma 5 to 10 cm (or more), a conformational radiation with or without intensity modulation is performed. Stereotactic body radiotherapy (SBRT) is being evaluated and is increasingly proposed as an alternative to radiofrequency ablative treatment for primary or secondary tumors (typically less than 5 cm). Tumor (and liver) movements induced by respiratory motions must be taken into account. Strict dosimetric criteria must be met with particular attention to the dose–volume histograms to liver and the hollow organs, including cases of SBRT." @default.
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- W2460469759 date "2016-09-01" @default.
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- W2460469759 title "Radiothérapie des tumeurs hépatiques" @default.
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- W2460469759 doi "https://doi.org/10.1016/j.canrad.2016.07.019" @default.
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