Matches in SemOpenAlex for { <https://semopenalex.org/work/W2460519005> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2460519005 endingPage "157" @default.
- W2460519005 startingPage "147" @default.
- W2460519005 abstract "Due to the lack of vaccine, the HIV epidemic is still uncontrolled. Use of antiretrovirals (ARV) for prevention, successfully implemented to prevent mother-to-child transmission of HIV, is a new avenue to control the epidemic. One approach is to treat all patients diagnosed with HIV, and suppress viremia and transmission to their partner. Another strategy is the use of ARV as a pre-exposition prophylaxis (PrEP) in HIV-negative at risk individuals. Oral tenofovir (TDF) ± emtricitabine (FTC) is the elected drug regimen for PrEP, given its safety, its long intracellular half-life and a high diffusion into mucosal entry sites. PrEP was investigated in randomized trials of oral or local gel given daily or at time of sexual intercourse in high-risk populations. PrEP efficacy is strongly correlated to adherence and concentrations of ARV. Adverse events have been infrequent. Selection of FTC-resistant strains has been mainly reported in undiagnosed HIV-infected participants using PrEP. PrEP is now strongly recommended by WHO in prevention programs for HIV in order to control the epidemic by 2030." @default.
- W2460519005 created "2016-07-22" @default.
- W2460519005 creator A5022180654 @default.
- W2460519005 creator A5046238828 @default.
- W2460519005 creator A5066083849 @default.
- W2460519005 creator A5074366002 @default.
- W2460519005 date "2016-06-01" @default.
- W2460519005 modified "2023-09-30" @default.
- W2460519005 title "La prévention pré-exposition au VIH-1 par les antirétroviraux, la PrEP." @default.
- W2460519005 doi "https://doi.org/10.1684/vir.2016.0658" @default.
- W2460519005 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33065894" @default.
- W2460519005 hasPublicationYear "2016" @default.
- W2460519005 type Work @default.
- W2460519005 sameAs 2460519005 @default.
- W2460519005 citedByCount "0" @default.
- W2460519005 crossrefType "journal-article" @default.
- W2460519005 hasAuthorship W2460519005A5022180654 @default.
- W2460519005 hasAuthorship W2460519005A5046238828 @default.
- W2460519005 hasAuthorship W2460519005A5066083849 @default.
- W2460519005 hasAuthorship W2460519005A5074366002 @default.
- W2460519005 hasConcept C119599485 @default.
- W2460519005 hasConcept C126322002 @default.
- W2460519005 hasConcept C127413603 @default.
- W2460519005 hasConcept C142462285 @default.
- W2460519005 hasConcept C159047783 @default.
- W2460519005 hasConcept C197746943 @default.
- W2460519005 hasConcept C197934379 @default.
- W2460519005 hasConcept C2776185481 @default.
- W2460519005 hasConcept C2776939746 @default.
- W2460519005 hasConcept C2776983459 @default.
- W2460519005 hasConcept C2779344132 @default.
- W2460519005 hasConcept C2779496540 @default.
- W2460519005 hasConcept C2779778239 @default.
- W2460519005 hasConcept C2781413609 @default.
- W2460519005 hasConcept C2993143319 @default.
- W2460519005 hasConcept C3013748606 @default.
- W2460519005 hasConcept C3019340110 @default.
- W2460519005 hasConcept C71924100 @default.
- W2460519005 hasConcept C761482 @default.
- W2460519005 hasConceptScore W2460519005C119599485 @default.
- W2460519005 hasConceptScore W2460519005C126322002 @default.
- W2460519005 hasConceptScore W2460519005C127413603 @default.
- W2460519005 hasConceptScore W2460519005C142462285 @default.
- W2460519005 hasConceptScore W2460519005C159047783 @default.
- W2460519005 hasConceptScore W2460519005C197746943 @default.
- W2460519005 hasConceptScore W2460519005C197934379 @default.
- W2460519005 hasConceptScore W2460519005C2776185481 @default.
- W2460519005 hasConceptScore W2460519005C2776939746 @default.
- W2460519005 hasConceptScore W2460519005C2776983459 @default.
- W2460519005 hasConceptScore W2460519005C2779344132 @default.
- W2460519005 hasConceptScore W2460519005C2779496540 @default.
- W2460519005 hasConceptScore W2460519005C2779778239 @default.
- W2460519005 hasConceptScore W2460519005C2781413609 @default.
- W2460519005 hasConceptScore W2460519005C2993143319 @default.
- W2460519005 hasConceptScore W2460519005C3013748606 @default.
- W2460519005 hasConceptScore W2460519005C3019340110 @default.
- W2460519005 hasConceptScore W2460519005C71924100 @default.
- W2460519005 hasConceptScore W2460519005C761482 @default.
- W2460519005 hasIssue "3" @default.
- W2460519005 hasLocation W24605190051 @default.
- W2460519005 hasOpenAccess W2460519005 @default.
- W2460519005 hasPrimaryLocation W24605190051 @default.
- W2460519005 hasRelatedWork W1771085506 @default.
- W2460519005 hasRelatedWork W2009609351 @default.
- W2460519005 hasRelatedWork W2021002635 @default.
- W2460519005 hasRelatedWork W2088807081 @default.
- W2460519005 hasRelatedWork W2134624998 @default.
- W2460519005 hasRelatedWork W2149708245 @default.
- W2460519005 hasRelatedWork W2460519005 @default.
- W2460519005 hasRelatedWork W2503316431 @default.
- W2460519005 hasRelatedWork W2975872300 @default.
- W2460519005 hasRelatedWork W2976818300 @default.
- W2460519005 hasVolume "20" @default.
- W2460519005 isParatext "false" @default.
- W2460519005 isRetracted "false" @default.
- W2460519005 magId "2460519005" @default.
- W2460519005 workType "article" @default.