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- W2460754328 abstract "The effects of cholestane-3 beta, 5 alpha, 6 beta-triol (TriolC) and/or low magnesium on uptake, internalization, surface binding and degradation of 125I-LDL were investigated in cultured endothelial cells. TriolC (at a level of 1 microgram/ml and higher) or magnesium (at a level of 188 microM and lower) in cultured medium decreased significantly the uptake, internalization, surface binding and degradation of 125I-LDL. When TriolC and low magnesium were combined, the significant inhibitions of uptake, internalization, surface binding and degradation of 125I-LDL were also observed although by themselves at these levels (TriolC lower than 1 microgram/ml and magnesium higher than 188 microM) they had no obvious effects. Our work suggests that a combination of low magnesium and TriolC have additive inhibitive effects on uptake, internalization, surface binding and degradation of 125I-LDL." @default.
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- W2460754328 date "1999-06-01" @default.
- W2460754328 modified "2023-09-23" @default.
- W2460754328 title "The accentuating effect of low magnesium concentration on cholestane-3 beta, 5 alpha, 6 beta-triol-induced decrease of LDL uptake by cultured endothelial cells." @default.
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