Matches in SemOpenAlex for { <https://semopenalex.org/work/W2460777776> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W2460777776 endingPage "1794; author reply 1795" @default.
- W2460777776 startingPage "1794; author reply 1795" @default.
- W2460777776 abstract "Two problems must be considered in regard to the relationship between vaccinations and MS: Do vaccinations favour the first attack of MS? Do they increase the short- or long-term risk in patients with known disease? Answers to these questions are difficult due to the paucity of reported cases, our ignorance of the precise frequency of neurological adverse events in vaccines based on prospective studies, and finally by the lack of a well established pathophysiology. In most instances, the role of the vaccine is based on a temporal link between the injection and the onset of neurological disease, and more rarely to a positive reintroduction. Acute disseminated encephalomyelitis (ADEM), a monophasic and multifocal illness of the white and grey matter, has been observed following various viral or bacterial infections as well as vaccine injections for diseases such as pertussis, tetanus and yellow fever. The similarities between ADEM and experimental allergic encephalitis (EAE) are suggestive of an immunological process. In addition to the dramatic presentation of ADEM, more limited white matter involvement, such as optic neuritis or myelitis, has been reported following vaccine injections, and has occasionally been counted as the first attack of MS. In France, 25 million inhabitants, almost half of the population, were vaccinated against hepatitis B (HB) between 1991 and 1999. Several hundred cases of an acute central demyelinating event following HB vaccination were reported to the pharmacovigilance unit, leading to a modification of vaccination policy in the schools and the initiation of several studies designed to examine the possible relationship between the vaccine and the central demyelinating events. The results of these studies failed to establish the causality of the HB vaccine. Nevertheless, molecular mimicry between HB antigen(s) and one or more myelin proteins, or a non-specific activation of autoreactive lymphocytes, could constitute possible pathogenetic mechanisms for these adverse neurological events." @default.
- W2460777776 created "2016-07-22" @default.
- W2460777776 creator A5006513938 @default.
- W2460777776 date "2001-06-07" @default.
- W2460777776 modified "2023-09-23" @default.
- W2460777776 title "Vaccinations and multiple sclerosis." @default.
- W2460777776 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11396453" @default.
- W2460777776 hasPublicationYear "2001" @default.
- W2460777776 type Work @default.
- W2460777776 sameAs 2460777776 @default.
- W2460777776 citedByCount "2" @default.
- W2460777776 crossrefType "posted-content" @default.
- W2460777776 hasAuthorship W2460777776A5006513938 @default.
- W2460777776 hasConcept C118552586 @default.
- W2460777776 hasConcept C126322002 @default.
- W2460777776 hasConcept C187212893 @default.
- W2460777776 hasConcept C197934379 @default.
- W2460777776 hasConcept C203014093 @default.
- W2460777776 hasConcept C22070199 @default.
- W2460777776 hasConcept C2522874641 @default.
- W2460777776 hasConcept C2776572573 @default.
- W2460777776 hasConcept C2777704947 @default.
- W2460777776 hasConcept C2779134260 @default.
- W2460777776 hasConcept C2779328510 @default.
- W2460777776 hasConcept C2780640218 @default.
- W2460777776 hasConcept C2780775167 @default.
- W2460777776 hasConcept C2781137167 @default.
- W2460777776 hasConcept C2908647359 @default.
- W2460777776 hasConcept C57658597 @default.
- W2460777776 hasConcept C71924100 @default.
- W2460777776 hasConcept C83455156 @default.
- W2460777776 hasConcept C99454951 @default.
- W2460777776 hasConceptScore W2460777776C118552586 @default.
- W2460777776 hasConceptScore W2460777776C126322002 @default.
- W2460777776 hasConceptScore W2460777776C187212893 @default.
- W2460777776 hasConceptScore W2460777776C197934379 @default.
- W2460777776 hasConceptScore W2460777776C203014093 @default.
- W2460777776 hasConceptScore W2460777776C22070199 @default.
- W2460777776 hasConceptScore W2460777776C2522874641 @default.
- W2460777776 hasConceptScore W2460777776C2776572573 @default.
- W2460777776 hasConceptScore W2460777776C2777704947 @default.
- W2460777776 hasConceptScore W2460777776C2779134260 @default.
- W2460777776 hasConceptScore W2460777776C2779328510 @default.
- W2460777776 hasConceptScore W2460777776C2780640218 @default.
- W2460777776 hasConceptScore W2460777776C2780775167 @default.
- W2460777776 hasConceptScore W2460777776C2781137167 @default.
- W2460777776 hasConceptScore W2460777776C2908647359 @default.
- W2460777776 hasConceptScore W2460777776C57658597 @default.
- W2460777776 hasConceptScore W2460777776C71924100 @default.
- W2460777776 hasConceptScore W2460777776C83455156 @default.
- W2460777776 hasConceptScore W2460777776C99454951 @default.
- W2460777776 hasIssue "23" @default.
- W2460777776 hasLocation W24607777761 @default.
- W2460777776 hasOpenAccess W2460777776 @default.
- W2460777776 hasPrimaryLocation W24607777761 @default.
- W2460777776 hasRelatedWork W1987700102 @default.
- W2460777776 hasRelatedWork W2026072358 @default.
- W2460777776 hasRelatedWork W2040952287 @default.
- W2460777776 hasRelatedWork W2413157594 @default.
- W2460777776 hasRelatedWork W2460777776 @default.
- W2460777776 hasRelatedWork W2753327292 @default.
- W2460777776 hasRelatedWork W2770863219 @default.
- W2460777776 hasRelatedWork W2895143009 @default.
- W2460777776 hasRelatedWork W2905137679 @default.
- W2460777776 hasRelatedWork W2183628977 @default.
- W2460777776 hasVolume "344" @default.
- W2460777776 isParatext "false" @default.
- W2460777776 isRetracted "false" @default.
- W2460777776 magId "2460777776" @default.
- W2460777776 workType "article" @default.