FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2461081616> ?p ?o ?g. }

• W2461081616 endingPage "8379" @default.
• W2461081616 startingPage "8369" @default.
• W2461081616 abstract "Amphiphilic polyelectrolytes (APEs), exhibiting particular self-association properties in aqueous media, can be used in different industrial applications, including drug delivery systems. Their typical core–shell structure (micelle) depends on the balance of interactions between hydrophobic and ionizable monomer units. In this work, the structure of amphiphilic cationic random copolymers, obtained by employing different molar ratios of two acrylic monomers, one bearing in the side chain a tertiary amine (N,N-diethylethylendiamine, DED) and the other one a hydrophobic catecholic group (hydroxytyrosol, HTy), was investigated by atomistic molecular dynamics (MD) simulation, 1H NMR analysis, dynamic light scattering (DLS), and zeta potential measurements. The structures of p(AcDED-co-AcHTy) copolymers were compared with that of the cationic homopolymer (pAcDED). MD simulation showed a chain folding in water solution of all polymer materials consistent with the degree of hydrophobicity of the chain, that increases with the number of aromatic residues. This phenomenon was induced by the interaction between the charged amine groups with water and by the associated attraction between aromatic rings inside the molecule. In addition, the p(AcDED-co-AcHTy) 70/30 copolymer had a marked tendency to self-assemble as shown by the radial distribution function among catechol carbon atoms. Electrical conductivity measurements evidenced a micellar arragment for all of the synthesized copolymers, and specially for p(AcDED-co-AcHTy) 70/30, a flower micelle structure seem to be more likely. The stacking interactions among catecholic groups present in the side chain of the copolymers reduced the size and charge density specially for the p(AcDED-co-AcHTy) 70/30 copolymer. Finally, the good antimicrobial activity of all copolymers confirmed the right reached amphiphilic balance. Indeed, a considerable reduction of the minimum inhibitory concentration (from 100 μg/mL to 40 μg/mL for pAcDED and p(AcDED-co-AcHTy) 70/30, respectively) was obtained by introducing a hydrophobic group molar fraction of 0.3." @default.
• W2461081616 created "2016-07-22" @default.
• W2461081616 creator A5010107533 @default.
• W2461081616 creator A5012676277 @default.
• W2461081616 creator A5027115268 @default.
• W2461081616 creator A5056060581 @default.
• W2461081616 creator A5056863530 @default.
• W2461081616 creator A5061854548 @default.
• W2461081616 creator A5072755937 @default.
• W2461081616 creator A5080543721 @default.
• W2461081616 date "2015-06-24" @default.
• W2461081616 modified "2023-10-04" @default.
• W2461081616 title "Self-Assembly of Catecholic Moiety-Containing Cationic Random Acrylic Copolymers" @default.
• W2461081616 cites W1575057984 @default.
• W2461081616 cites W1969585687 @default.
• W2461081616 cites W1970438751 @default.
• W2461081616 cites W1983908683 @default.
• W2461081616 cites W1984309150 @default.
• W2461081616 cites W1984349429 @default.
• W2461081616 cites W1986286007 @default.
• W2461081616 cites W1992849030 @default.
• W2461081616 cites W1995813538 @default.
• W2461081616 cites W1996857325 @default.
• W2461081616 cites W1996992225 @default.
• W2461081616 cites W2003949305 @default.
• W2461081616 cites W2008517160 @default.
• W2461081616 cites W2015639733 @default.
• W2461081616 cites W2017656146 @default.
• W2461081616 cites W2020045592 @default.
• W2461081616 cites W2029642477 @default.
• W2461081616 cites W2030243013 @default.
• W2461081616 cites W2032688587 @default.
• W2461081616 cites W2037382830 @default.
• W2461081616 cites W2046885100 @default.
• W2461081616 cites W2048228859 @default.
• W2461081616 cites W2048722166 @default.
• W2461081616 cites W2049622924 @default.
• W2461081616 cites W2050165926 @default.
• W2461081616 cites W2055029949 @default.
• W2461081616 cites W2055630226 @default.
• W2461081616 cites W2064683586 @default.
• W2461081616 cites W2066611789 @default.
• W2461081616 cites W2070231716 @default.
• W2461081616 cites W2070599961 @default.
• W2461081616 cites W2071447376 @default.
• W2461081616 cites W2074186021 @default.
• W2461081616 cites W2079189662 @default.
• W2461081616 cites W2080116234 @default.
• W2461081616 cites W2082642459 @default.
• W2461081616 cites W2086094111 @default.
• W2461081616 cites W2091978917 @default.
• W2461081616 cites W2094446407 @default.
• W2461081616 cites W2107428341 @default.
• W2461081616 cites W2126512081 @default.
• W2461081616 cites W2126957299 @default.
• W2461081616 cites W2147993766 @default.
• W2461081616 cites W2159879360 @default.
• W2461081616 cites W2169678694 @default.
• W2461081616 cites W2170103495 @default.
• W2461081616 cites W2171112364 @default.
• W2461081616 cites W2171268876 @default.
• W2461081616 cites W2171376065 @default.
• W2461081616 cites W2325229788 @default.
• W2461081616 cites W2329846226 @default.
• W2461081616 cites W2330503753 @default.
• W2461081616 cites W2493657608 @default.
• W2461081616 cites W4211116418 @default.
• W2461081616 doi "https://doi.org/10.1021/acs.jpcb.5b05022" @default.
• W2461081616 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26075948" @default.
• W2461081616 hasPublicationYear "2015" @default.
• W2461081616 type Work @default.
• W2461081616 sameAs 2461081616 @default.
• W2461081616 citedByCount "16" @default.
• W2461081616 countsByYear W24610816162015 @default.
• W2461081616 countsByYear W24610816162016 @default.
• W2461081616 countsByYear W24610816162017 @default.
• W2461081616 countsByYear W24610816162018 @default.
• W2461081616 countsByYear W24610816162020 @default.
• W2461081616 countsByYear W24610816162021 @default.
• W2461081616 countsByYear W24610816162022 @default.
• W2461081616 countsByYear W24610816162023 @default.
• W2461081616 crossrefType "journal-article" @default.
• W2461081616 hasAuthorship W2461081616A5010107533 @default.
• W2461081616 hasAuthorship W2461081616A5012676277 @default.
• W2461081616 hasAuthorship W2461081616A5027115268 @default.
• W2461081616 hasAuthorship W2461081616A5056060581 @default.
• W2461081616 hasAuthorship W2461081616A5056863530 @default.
• W2461081616 hasAuthorship W2461081616A5061854548 @default.
• W2461081616 hasAuthorship W2461081616A5072755937 @default.
• W2461081616 hasAuthorship W2461081616A5080543721 @default.
• W2461081616 hasConcept C11268172 @default.
• W2461081616 hasConcept C127413603 @default.
• W2461081616 hasConcept C153356533 @default.
• W2461081616 hasConcept C155672457 @default.
• W2461081616 hasConcept C15920480 @default.
• W2461081616 hasConcept C166940927 @default.
• W2461081616 hasConcept C171250308 @default.
• W2461081616 hasConcept C178790620 @default.

• next