FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2461350706> ?p ?o ?g. }

• W2461350706 endingPage "54837" @default.
• W2461350706 startingPage "54825" @default.
• W2461350706 abstract "// Sang-Yong Shin 1 , Seung-Tae Lee 2 , Hee-Jin Kim 3 , Eun Hae Cho 5 , Jong-Won Kim 3 , Silvia Park 4 , Chul Won Jung 4 , Sun-Hee Kim 3 1 Department of Laboratory Medicine, Center for Diagnostic Oncology, Hospital and Research Institute, National Cancer Center, Goyang, Korea 2 Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea 3 Department of Laboratory Medicine & Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea 4 Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea 5 Green Cross Genome, Yongin, Korea Correspondence to: Seung-Tae Lee, email: lee.st@yuhs.ac Sun-Hee Kim, email: sunnyhk@skku.edu Keywords: acute myeloid leukemia, mutation, next generation sequencing, DNMT3A Received: October 19, 2015     Accepted: May 13, 2016     Published: June 23, 2016 ABSTRACT We selected 19 significantly-mutated genes in AMLs, including FLT3 , DNMT3A, NPM1, TET2, RUNX1, CEBPA, WT1, IDH1, IDH2, NRAS, ASXL1, SETD2, PTPN11, TP53, KIT, JAK2, KRAS, BRAF and CBL , and performed massively parallel sequencing for 114 patients with acute myeloid leukemias, mainly including those with normal karyotypes (CN-AML). More than 80% of patients had at least one mutation in the genes tested. DNMT3A mutation was significantly associated with adverse outcome in addition to conventional risk stratification such as the European LeukemiaNet (ELN) classification. We observed clinical usefulness of mutation testing on multiple target genes and the association with disease subgroups, clinical features and prognosis in AMLs." @default.
• W2461350706 created "2016-07-22" @default.
• W2461350706 creator A5015112169 @default.
• W2461350706 creator A5023642117 @default.
• W2461350706 creator A5033356298 @default.
• W2461350706 creator A5045574858 @default.
• W2461350706 creator A5055461839 @default.
• W2461350706 creator A5057714776 @default.
• W2461350706 creator A5062627428 @default.
• W2461350706 creator A5067818349 @default.
• W2461350706 date "2016-06-23" @default.
• W2461350706 modified "2023-09-30" @default.
• W2461350706 title "Mutation profiling of 19 candidate genes in acute myeloid leukemia suggests significance of <i>DNMT3A</i> mutations" @default.
• W2461350706 cites W1492609361 @default.
• W2461350706 cites W1563940013 @default.
• W2461350706 cites W1855200385 @default.
• W2461350706 cites W187589025 @default.
• W2461350706 cites W1976129634 @default.
• W2461350706 cites W1977209559 @default.
• W2461350706 cites W1980740976 @default.
• W2461350706 cites W1987198309 @default.
• W2461350706 cites W2004739140 @default.
• W2461350706 cites W2018240559 @default.
• W2461350706 cites W2021341670 @default.
• W2461350706 cites W2021839918 @default.
• W2461350706 cites W2030736903 @default.
• W2461350706 cites W2032634544 @default.
• W2461350706 cites W2043216151 @default.
• W2461350706 cites W2043471007 @default.
• W2461350706 cites W2045587009 @default.
• W2461350706 cites W2046069452 @default.
• W2461350706 cites W2059886913 @default.
• W2461350706 cites W2063260586 @default.
• W2461350706 cites W2076907935 @default.
• W2461350706 cites W2080433813 @default.
• W2461350706 cites W2082099618 @default.
• W2461350706 cites W2082365047 @default.
• W2461350706 cites W2084777221 @default.
• W2461350706 cites W2099880635 @default.
• W2461350706 cites W2102582070 @default.
• W2461350706 cites W2102616711 @default.
• W2461350706 cites W2103930081 @default.
• W2461350706 cites W2108484319 @default.
• W2461350706 cites W2109150359 @default.
• W2461350706 cites W2109554035 @default.
• W2461350706 cites W2113371461 @default.
• W2461350706 cites W2115707319 @default.
• W2461350706 cites W2116858301 @default.
• W2461350706 cites W2124715997 @default.
• W2461350706 cites W2131072337 @default.
• W2461350706 cites W2131508453 @default.
• W2461350706 cites W2134061682 @default.
• W2461350706 cites W2151924639 @default.
• W2461350706 cites W2155104532 @default.
• W2461350706 cites W2157326360 @default.
• W2461350706 cites W2159355068 @default.
• W2461350706 cites W2160123981 @default.
• W2461350706 cites W2338735643 @default.
• W2461350706 doi "https://doi.org/10.18632/oncotarget.10240" @default.
• W2461350706 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5342384" @default.
• W2461350706 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27359055" @default.
• W2461350706 hasPublicationYear "2016" @default.
• W2461350706 type Work @default.
• W2461350706 sameAs 2461350706 @default.
• W2461350706 citedByCount "21" @default.
• W2461350706 countsByYear W24613507062017 @default.
• W2461350706 countsByYear W24613507062018 @default.
• W2461350706 countsByYear W24613507062019 @default.
• W2461350706 countsByYear W24613507062020 @default.
• W2461350706 countsByYear W24613507062021 @default.
• W2461350706 countsByYear W24613507062022 @default.
• W2461350706 countsByYear W24613507062023 @default.
• W2461350706 crossrefType "journal-article" @default.
• W2461350706 hasAuthorship W2461350706A5015112169 @default.
• W2461350706 hasAuthorship W2461350706A5023642117 @default.
• W2461350706 hasAuthorship W2461350706A5033356298 @default.
• W2461350706 hasAuthorship W2461350706A5045574858 @default.
• W2461350706 hasAuthorship W2461350706A5055461839 @default.
• W2461350706 hasAuthorship W2461350706A5057714776 @default.
• W2461350706 hasAuthorship W2461350706A5062627428 @default.
• W2461350706 hasAuthorship W2461350706A5067818349 @default.
• W2461350706 hasBestOaLocation W24613507061 @default.
• W2461350706 hasConcept C104317684 @default.
• W2461350706 hasConcept C121608353 @default.
• W2461350706 hasConcept C126322002 @default.
• W2461350706 hasConcept C143998085 @default.
• W2461350706 hasConcept C194409129 @default.
• W2461350706 hasConcept C21790070 @default.
• W2461350706 hasConcept C2483381 @default.
• W2461350706 hasConcept C2778729363 @default.
• W2461350706 hasConcept C2781187634 @default.
• W2461350706 hasConcept C30481170 @default.
• W2461350706 hasConcept C31734879 @default.
• W2461350706 hasConcept C45091340 @default.
• W2461350706 hasConcept C501734568 @default.
• W2461350706 hasConcept C526805850 @default.
• W2461350706 hasConcept C53226629 @default.
• W2461350706 hasConcept C54355233 @default.

• next