Matches in SemOpenAlex for { <https://semopenalex.org/work/W2461570401> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W2461570401 endingPage "853" @default.
- W2461570401 startingPage "853" @default.
- W2461570401 abstract "The vasodilatory response to passive leg movement (PLM) is predominantly nitric oxide (NO) mediated. Due to reduced NO bioavailability with advancing age, PLM-induced vasodilation is attenuated in older sedentary subjects. PURPOSE: We sought to determine the impact of varying levels of physical activity on PLM-induced vasodilation, and therefore NO bioavailability, in older subjects. METHODS: PLM was performed on four subject groups (young sedentary (YS), 23 ± 1 yrs, n = 12; old sedentary (OS), 73 ± 2 yrs, n = 12; old active (OA), 71 ± 2 yrs, n = 10; old endurance trained (OT), 72 ± 1 yrs, n = 10) in the upright-seated posture. Central and peripheral hemodynamic responses were determined second-by-second with finger photoplethysmography and Doppler ultrasound, respectively. RESULTS: Peak VO2 was significantly different between all subject groups (YS = 42 ± 3, OS = 26 ± 2, OA = 34 ± 2, OT = 52 ± 2 ml/kg/min; P < 0.05). PLM-induced peak change in leg vascular conductance (ΔLVCpeak) was significantly attenuated in OS compared to YS (OS: 4.4 ± 0.8, YS: 11.8 ± 1.3 ml/min/mmHg; P < 0.05). Both OA and OT groups demonstrated augmented ΔLVCpeak compared to OS (OA: 7.3 ± 0.8, OT: 7.6 ± 0.9 ml/min/mmHg; P < 0.05). However, OA and OT groups were not different (P = 0.82), and remained attenuated compared to YS (P < 0.05). The rapid vasodilatory response (slope of LVC over time; ml/min/mmHg/s), also thought to be partially NO-dependent, was not different between YS, OA, and OT (YS: 1.08 ± 0.14, OA: 0.75 ± 0.10, OT: 0.79 ± 0.14 ml/min/mmHg/s; P < 0.05), but was decreased in OS compared to the other three groups (0.42 ± 0.06 ml/min/mmHg/s; P < 0.05). CONCLUSIONS: These data suggest that remaining physically active during aging likely augments NO-mediated vascular function. However, physical activity, even at levels achieved by highly trained older individuals, failed to fully restore vasodilatory responses to that of the young." @default.
- W2461570401 created "2016-07-22" @default.
- W2461570401 creator A5016791114 @default.
- W2461570401 creator A5025541198 @default.
- W2461570401 creator A5031447744 @default.
- W2461570401 creator A5032525742 @default.
- W2461570401 creator A5057187042 @default.
- W2461570401 creator A5065944938 @default.
- W2461570401 creator A5069922151 @default.
- W2461570401 date "2015-05-01" @default.
- W2461570401 modified "2023-09-25" @default.
- W2461570401 title "Physical Activity And Passive Leg Movement-Induced Vasodilation" @default.
- W2461570401 doi "https://doi.org/10.1249/01.mss.0000479040.38732.69" @default.
- W2461570401 hasPublicationYear "2015" @default.
- W2461570401 type Work @default.
- W2461570401 sameAs 2461570401 @default.
- W2461570401 citedByCount "0" @default.
- W2461570401 crossrefType "journal-article" @default.
- W2461570401 hasAuthorship W2461570401A5016791114 @default.
- W2461570401 hasAuthorship W2461570401A5025541198 @default.
- W2461570401 hasAuthorship W2461570401A5031447744 @default.
- W2461570401 hasAuthorship W2461570401A5032525742 @default.
- W2461570401 hasAuthorship W2461570401A5057187042 @default.
- W2461570401 hasAuthorship W2461570401A5065944938 @default.
- W2461570401 hasAuthorship W2461570401A5069922151 @default.
- W2461570401 hasConcept C106131492 @default.
- W2461570401 hasConcept C116390426 @default.
- W2461570401 hasConcept C120770815 @default.
- W2461570401 hasConcept C126322002 @default.
- W2461570401 hasConcept C164705383 @default.
- W2461570401 hasConcept C178853913 @default.
- W2461570401 hasConcept C181389837 @default.
- W2461570401 hasConcept C31972630 @default.
- W2461570401 hasConcept C41008148 @default.
- W2461570401 hasConcept C519581460 @default.
- W2461570401 hasConcept C71924100 @default.
- W2461570401 hasConcept C98274493 @default.
- W2461570401 hasConceptScore W2461570401C106131492 @default.
- W2461570401 hasConceptScore W2461570401C116390426 @default.
- W2461570401 hasConceptScore W2461570401C120770815 @default.
- W2461570401 hasConceptScore W2461570401C126322002 @default.
- W2461570401 hasConceptScore W2461570401C164705383 @default.
- W2461570401 hasConceptScore W2461570401C178853913 @default.
- W2461570401 hasConceptScore W2461570401C181389837 @default.
- W2461570401 hasConceptScore W2461570401C31972630 @default.
- W2461570401 hasConceptScore W2461570401C41008148 @default.
- W2461570401 hasConceptScore W2461570401C519581460 @default.
- W2461570401 hasConceptScore W2461570401C71924100 @default.
- W2461570401 hasConceptScore W2461570401C98274493 @default.
- W2461570401 hasIssue "5S" @default.
- W2461570401 hasLocation W24615704011 @default.
- W2461570401 hasOpenAccess W2461570401 @default.
- W2461570401 hasPrimaryLocation W24615704011 @default.
- W2461570401 hasRelatedWork W1197780189 @default.
- W2461570401 hasRelatedWork W1962572796 @default.
- W2461570401 hasRelatedWork W2011347913 @default.
- W2461570401 hasRelatedWork W2035474875 @default.
- W2461570401 hasRelatedWork W2036078545 @default.
- W2461570401 hasRelatedWork W2049397185 @default.
- W2461570401 hasRelatedWork W2147559323 @default.
- W2461570401 hasRelatedWork W2159512267 @default.
- W2461570401 hasRelatedWork W2304633692 @default.
- W2461570401 hasRelatedWork W2399063111 @default.
- W2461570401 hasVolume "47" @default.
- W2461570401 isParatext "false" @default.
- W2461570401 isRetracted "false" @default.
- W2461570401 magId "2461570401" @default.
- W2461570401 workType "article" @default.