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• W2462078257 abstract "High-risk atherosclerotic plaques as thin cap fibroatheroma (TCFA) are frequently located in coronary regions with low shear stress [ 1 Malek A. Alper S.L. Izumo S. Hemodynamic shear stress and its role in atherosclerosis. J. Am. Med. Assoc. 1999; 282: 2035-2042 Crossref PubMed Scopus (2699) Google Scholar , 2 Vergallo R. Papafaklis M.I. Yonetsu T. et al. Endothelial shear stress and coronary plaque characteristics in humans: combined frequency-domain optical coherence tomography and computational fluid dynamics study. Circ. Cardiovasc. Imaging. 2014; 7: 905-911 Crossref PubMed Scopus (74) Google Scholar ], as coronary bifurcation and in particular left main (LM) bifurcation [ [3] Gerber T.C. Erbel R. Go¨rge G. J G. Rupprecht H.J. Meyer J. Extent of atherosclerosis and remodeling of the left main coronary artery determined by intravascular ultrasound. Am. J. Cardiol. 1994; 73: 666-671 Abstract Full Text PDF PubMed Scopus (109) Google Scholar ]. Previous invasive imaging studies on LM plaque characterization by intravascular ultrasound (IVUS) reported that LM carina is usually spared and that the disease is generally extended from LM into the distal branches [ [4] Oviedo C. Maehara A. Mintz G.S. et al. Intravascular ultrasound classification of plaque distribution in left main coronary artery bifurcations: where is the plaque really located?. Circ. Cardiovasc. Interv. 2010; 3: 105-112 Crossref PubMed Scopus (145) Google Scholar ]. Frequency domain-optical coherence tomography (FD-OCT) is a high resolution imaging modality that allows high-quality visualization of inner vessel wall structure and accurate measurement of vascular microstructures such as the fibrous cap [ [5] Kume T. Akasaka T. Kawamoto T. et al. Measurement of the thickness of the fibrous cap by optical coherence tomography. Am. Heart J. 2006; 152: 755e1-755e4 Abstract Full Text Full Text PDF Scopus (223) Google Scholar ]. FD-OCT assessment of LM bifurcation is feasible and provides adequate imaging with detailed morphological information [ [6] Burzotta F. Dato I. Trani C. et al. Frequency-domain optical coherence tomography to assess non-ostial left main coronary artery disease. EuroIntervention. 2015; 10: e1-e8 Crossref PubMed Scopus (34) Google Scholar ]. In the present study, we sought to evaluate the geographical distribution and morphology of atherosclerotic plaques in angiographically-ambiguous LM bifurcation using FD-OCT." @default.
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• W2462078257 date "2016-10-01" @default.
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• W2462078257 title "Angiographically intermediate left main bifurcation disease assessment by frequency domain optical coherence tomography (FD-OCT)" @default.
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• W2462078257 doi "https://doi.org/10.1016/j.ijcard.2016.06.260" @default.
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