Matches in SemOpenAlex for { <https://semopenalex.org/work/W2462361007> ?p ?o ?g. }
- W2462361007 abstract "In a eukaryotic cell, each messenger RNA ( mRNA ) is bound to a variety of proteins to form an mRNA –protein complex ( mRNP ). Together, these proteins impact nearly every step in the life cycle of an mRNA and are critical for the proper control of gene expression. In the cytoplasm, for instance, mRNPs affect mRNA translatability and stability and provide regulation of specific transcripts as well as global, transcriptome‐wide control. mRNPs are complex, diverse, and dynamic, and so they have been a challenge to understand. But the advent of high‐throughput sequencing technology has heralded a new era in the study of mRNPs . Here, I will discuss general principles of cytoplasmic mRNP organization and regulation. Using microRNA ‐mediated repression as a case study, I will focus on common themes in mRNPs and highlight the interplay between mRNP composition and posttranscriptional regulation. mRNPs are an important control point in regulating gene expression, and while the study of these fascinating complexes presents remaining challenges, recent advances provide a critical lens for deciphering gene regulation. WIREs RNA 2017, 8:e1369. doi: 10.1002/wrna.1369 This article is categorized under: RNA Interactions with Proteins and Other Molecules > Protein–RNA Interactions: Functional Implications Translation > Translation Regulation RNA Turnover and Surveillance > Turnover/Surveillance Mechanisms" @default.
- W2462361007 created "2016-07-22" @default.
- W2462361007 creator A5082640946 @default.
- W2462361007 date "2016-06-21" @default.
- W2462361007 modified "2023-10-17" @default.
- W2462361007 title "The organization and regulation of <scp>mRNA</scp> –protein complexes" @default.
- W2462361007 cites W126837237 @default.
- W2462361007 cites W141311245 @default.
- W2462361007 cites W1523693806 @default.
- W2462361007 cites W1585169926 @default.
- W2462361007 cites W1744683414 @default.
- W2462361007 cites W1758820812 @default.
- W2462361007 cites W1807212217 @default.
- W2462361007 cites W1831176116 @default.
- W2462361007 cites W1865224608 @default.
- W2462361007 cites W1947010805 @default.
- W2462361007 cites W1951632364 @default.
- W2462361007 cites W1958284284 @default.
- W2462361007 cites W1963553964 @default.
- W2462361007 cites W1964727443 @default.
- W2462361007 cites W1967356824 @default.
- W2462361007 cites W1969412365 @default.
- W2462361007 cites W1969974585 @default.
- W2462361007 cites W1971754292 @default.
- W2462361007 cites W1974005002 @default.
- W2462361007 cites W1974717031 @default.
- W2462361007 cites W1975120493 @default.
- W2462361007 cites W1976612131 @default.
- W2462361007 cites W1978337436 @default.
- W2462361007 cites W1981074253 @default.
- W2462361007 cites W1981629946 @default.
- W2462361007 cites W1986911150 @default.
- W2462361007 cites W1988163167 @default.
- W2462361007 cites W1991588710 @default.
- W2462361007 cites W1992941735 @default.
- W2462361007 cites W1993147686 @default.
- W2462361007 cites W1995224771 @default.
- W2462361007 cites W1996157637 @default.
- W2462361007 cites W1998132778 @default.
- W2462361007 cites W1998819524 @default.
- W2462361007 cites W2003993220 @default.
- W2462361007 cites W2004070918 @default.
- W2462361007 cites W2004943023 @default.
- W2462361007 cites W2005300549 @default.
- W2462361007 cites W2005433767 @default.
- W2462361007 cites W2006254819 @default.
- W2462361007 cites W2006691081 @default.
- W2462361007 cites W2008410413 @default.
- W2462361007 cites W2008509160 @default.
- W2462361007 cites W2010088075 @default.
- W2462361007 cites W2010309470 @default.
- W2462361007 cites W2011239877 @default.
- W2462361007 cites W2013310179 @default.
- W2462361007 cites W2013321787 @default.
- W2462361007 cites W2017653670 @default.
- W2462361007 cites W2019696945 @default.
- W2462361007 cites W2019824435 @default.
- W2462361007 cites W2020377181 @default.
- W2462361007 cites W2026570544 @default.
- W2462361007 cites W2026570758 @default.
- W2462361007 cites W2027740340 @default.
- W2462361007 cites W2031495818 @default.
- W2462361007 cites W2031707270 @default.
- W2462361007 cites W2035792284 @default.
- W2462361007 cites W2041326730 @default.
- W2462361007 cites W2041389211 @default.
- W2462361007 cites W2041440237 @default.
- W2462361007 cites W2041770101 @default.
- W2462361007 cites W2042286349 @default.
- W2462361007 cites W2042673698 @default.
- W2462361007 cites W2043158983 @default.
- W2462361007 cites W2047188621 @default.
- W2462361007 cites W2047733032 @default.
- W2462361007 cites W2048728930 @default.
- W2462361007 cites W2048731469 @default.
- W2462361007 cites W2049141744 @default.
- W2462361007 cites W2049672413 @default.
- W2462361007 cites W2049830784 @default.
- W2462361007 cites W2050642406 @default.
- W2462361007 cites W2052991419 @default.
- W2462361007 cites W2053003053 @default.
- W2462361007 cites W2057532472 @default.
- W2462361007 cites W2059073003 @default.
- W2462361007 cites W2061791098 @default.
- W2462361007 cites W2063394028 @default.
- W2462361007 cites W2065023490 @default.
- W2462361007 cites W2072770570 @default.
- W2462361007 cites W2075559286 @default.
- W2462361007 cites W2076304484 @default.
- W2462361007 cites W2077584262 @default.
- W2462361007 cites W2077614707 @default.
- W2462361007 cites W2080977835 @default.
- W2462361007 cites W2082658854 @default.
- W2462361007 cites W2083381199 @default.
- W2462361007 cites W2087895896 @default.
- W2462361007 cites W2088215815 @default.
- W2462361007 cites W2088399865 @default.
- W2462361007 cites W2090860878 @default.
- W2462361007 cites W2094182822 @default.
- W2462361007 cites W2095370567 @default.