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• W2462584857 abstract "Prolonged sitting is associated with a risk of cardiovascular diseases, whereas activity breaks during sitting can prevent a decline in the arterial function. However, less is known about the exercise modes, intensity, duration, or frequency of active breaks. PURPOSE: The aim of this study was to investigate the effects of active break frequency on the vascular endothelial function as determined by flow-mediated vasodilation (FMD). METHODS: Seven healthy recreationally active adult males were studied under three experimental trials: a 3-hour uninterrupted period of sitting (SIT), a 3-hour period of sitting with 50W--cycling for 10min at 1h (ACT1), and a 3-hour period of sitting with the same exercises at 1h and 2h (ACT2). Before and after the three experimental trials, the brachial systolic and diastolic blood pressure (SBP, DBP) were measured using a volume-plethysmographic apparatus in the supine position. In order to measure FMD, forearm cuff inflation to 50 mmHg over their SBP for five minutes and subsequent deflation were also performed. The measurements of the right brachial artery diameter were taken using a high-resolution ultrasound device. The FMD was then estimated as the percent change in the arterial diameter over the baseline value at maximal dilation during reactive hyperemia. RESULTS: In the ACT2 trial, there was no significant change in FMD (before, 8.0±0.5%; immediately after, 8.5±0.6%; 30min after, 8.2±0.6%). However, there were significant declines in FMD in both SIT (before, 8.1±0.3%; immediately after, 7.4±0.4%; 30min after, 7.4±0.5%, p<0.05) and ACT1 (before, 8.1±0.3%; immediately after, 7.6±0.4%; 30min after, 7.5±0.4%, p<0.05). In the SBP/DBP, no significant changes were found throughout the three trials. CONCLUSIONS: Compared with once/no active breaks, two active breaks during a 3-hour sitting period are thus considered to be useful to prevent a decline in FMD. These findings support the idea that more active breaks protect the vascular endothelial function and may reduce the risk of cardiovascular diseases." @default.
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• W2462584857 date "2016-05-01" @default.
• W2462584857 modified "2023-10-16" @default.
• W2462584857 title "Influence Of Active Frequency During Sitting On The Vascular Endothelial Function" @default.
• W2462584857 doi "https://doi.org/10.1249/01.mss.0000488061.10182.f3" @default.
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