Matches in SemOpenAlex for { <https://semopenalex.org/work/W2462591496> ?p ?o ?g. }
Showing items 1 to 53 of
53
with 100 items per page.
- W2462591496 endingPage "30" @default.
- W2462591496 startingPage "25" @default.
- W2462591496 abstract "AIMS The impact of the chronic obstructive pulmonary disease (COPD) severity on the number of exacerbations, and the interdependence of COPD and some concomitant diseases were studied in chronic pulmonary patients. In order to determine the actual influence of some risk factors and comorbidity on the course of COPD, we conducted a study in two family medicine consulting offices, one in the city of Split and the other on the island of Brac. METHODS This retrospective study included a sample of 64 subjects, mean age 64.43 years, divided into two groups of 32 subjects each (group 1 and group 2). After taking history data and clinical examination, spirometry was performed. The severity of COPD was determined on the basis of lung function tests. RESULTS There were 15 (46.9%) smokers in group 1, seven of them former smokers, and 20 (65.6%) smokers in group 2, eight of them former smokers. The groups differed significantly according to the mean number of annual exacerbations (1.3 in group 1 and 2.4 in group 2; p < 0.001). The frequency of exacerbations was higher in smokers and depended on the stage of COPD. If COPD was more severe, the exacerbations were more frequent and influenced the progression of irreversible functional changes on the lungs. Productive cough was more frequent in smokers. The correlation of concomitant diseases and degree of COPD was found in group 2 (hypertension, r = 0.305; p = 0.014). In group 1, there was correlation between patient age and concomitant disease (cardiac arrhythmias, r = 0.307; p = 0.013), whereas in group 2 it was significant in case of hypertension (r = 0.474; p < 0.001) and cardiomyopathy (r = 0.301; p = 0.016). DISCUSSION Cigarette smoke causes chronic inflammatory changes in the lungs. In our study, the number of patients suffering from persistent cough accompanied by sputum was higher in group 2, which also comprised of more smokers, but differences between smokers and non-smokers according to this characteristic were not statistically significant. Study groups differed significantly according to the number of COPD exacerbations per year (with more exacerbations in the group with more smokers). In group 2, there was a correlation between COPD severity and hypertension. CONCLUSIONS Comorbidity of COPD and cardiovascular diseases was confirmed, along with correlation between age and cardiovascular complications in patients with COPD." @default.
- W2462591496 created "2016-07-22" @default.
- W2462591496 creator A5027315036 @default.
- W2462591496 creator A5065579490 @default.
- W2462591496 creator A5080450810 @default.
- W2462591496 date "2011-03-01" @default.
- W2462591496 modified "2023-09-24" @default.
- W2462591496 title "A study of comorbidity in patients with chronic obstructive pulmonary disease" @default.
- W2462591496 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21568071" @default.
- W2462591496 hasPublicationYear "2011" @default.
- W2462591496 type Work @default.
- W2462591496 sameAs 2462591496 @default.
- W2462591496 citedByCount "0" @default.
- W2462591496 crossrefType "journal-article" @default.
- W2462591496 hasAuthorship W2462591496A5027315036 @default.
- W2462591496 hasAuthorship W2462591496A5065579490 @default.
- W2462591496 hasAuthorship W2462591496A5080450810 @default.
- W2462591496 hasConcept C126322002 @default.
- W2462591496 hasConcept C1862650 @default.
- W2462591496 hasConcept C2776042228 @default.
- W2462591496 hasConcept C2776780178 @default.
- W2462591496 hasConcept C2777104659 @default.
- W2462591496 hasConcept C2779134260 @default.
- W2462591496 hasConcept C2779159551 @default.
- W2462591496 hasConcept C2779384505 @default.
- W2462591496 hasConcept C2780333948 @default.
- W2462591496 hasConcept C2992779976 @default.
- W2462591496 hasConcept C71924100 @default.
- W2462591496 hasConcept C75603125 @default.
- W2462591496 hasConceptScore W2462591496C126322002 @default.
- W2462591496 hasConceptScore W2462591496C1862650 @default.
- W2462591496 hasConceptScore W2462591496C2776042228 @default.
- W2462591496 hasConceptScore W2462591496C2776780178 @default.
- W2462591496 hasConceptScore W2462591496C2777104659 @default.
- W2462591496 hasConceptScore W2462591496C2779134260 @default.
- W2462591496 hasConceptScore W2462591496C2779159551 @default.
- W2462591496 hasConceptScore W2462591496C2779384505 @default.
- W2462591496 hasConceptScore W2462591496C2780333948 @default.
- W2462591496 hasConceptScore W2462591496C2992779976 @default.
- W2462591496 hasConceptScore W2462591496C71924100 @default.
- W2462591496 hasConceptScore W2462591496C75603125 @default.
- W2462591496 hasIssue "1" @default.
- W2462591496 hasLocation W24625914961 @default.
- W2462591496 hasLocation W24625914962 @default.
- W2462591496 hasOpenAccess W2462591496 @default.
- W2462591496 hasPrimaryLocation W24625914961 @default.
- W2462591496 hasVolume "65" @default.
- W2462591496 isParatext "false" @default.
- W2462591496 isRetracted "false" @default.
- W2462591496 magId "2462591496" @default.
- W2462591496 workType "article" @default.