Matches in SemOpenAlex for { <https://semopenalex.org/work/W2462604069> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2462604069 abstract "Purpose: Laparoscopic cholecystectomy is the treatment of choice for cholelithiasis. The pneumoperitoneum used for laparoscopic procedures results in significant hemodynamic and respiratory responses which might be harmful especially in cardiac patients. Clonidine has anti-hypertensive properties and augments the effects of anesthesia, thus it is a potentially an ideal agent to contain the stress response to pneumoperitoneum. We undertook this study to evaluate the clinical efficacy of oral clonidine premedication in patients undergoing laparoscopic cholecystectomies. Methods: 100 patients of ASA grade I–II, scheduled for elective laparoscopic cholecystectomy under general anaesthesia were randomly allocated to receive premedication with either oral clonidine 150 μg (Group I, n = 50) or placebo (Group II, n = 50) 90 minutes prior to induction. The patients were managed with a standard general anaesthetic. The two groups were compared with respect to haemodynamic parameters, pain and sedation scores and incidence of adverse effects like nausea-vomiting, shivering, hypotension, bradycardia etc. Results: Haemodynamic parameters i.e. pulse rate, systolic blood pressure, mean arterial pressure and diastolic blood pressure were significantly lower and stable in the clonidine group as compared to placebo group. Patients receiving oral clonidine premedication had less anxiety and no incidence of post –operative shivering. Clonidine also decreased need of postoperative analgesics and incidence of postoperative nausea / vomiting. Conclusion: From our study we found that clonidine in dose of 150 mcg can be used effectively and safely in ASA class I & II patients to control the hemodynamic changes which occur during laparoscopic cholecystectomy." @default.
- W2462604069 created "2016-07-22" @default.
- W2462604069 creator A5011157550 @default.
- W2462604069 creator A5026959042 @default.
- W2462604069 creator A5050801327 @default.
- W2462604069 creator A5069884507 @default.
- W2462604069 creator A5077612250 @default.
- W2462604069 date "2016-05-07" @default.
- W2462604069 modified "2023-09-24" @default.
- W2462604069 title "Effects of Oral Clonidine Premedication on Haemodynamic Responses During Laparoscopic Cholecystectomy –a Randomized Control Study" @default.
- W2462604069 hasPublicationYear "2016" @default.
- W2462604069 type Work @default.
- W2462604069 sameAs 2462604069 @default.
- W2462604069 citedByCount "1" @default.
- W2462604069 countsByYear W24626040692020 @default.
- W2462604069 crossrefType "journal-article" @default.
- W2462604069 hasAuthorship W2462604069A5011157550 @default.
- W2462604069 hasAuthorship W2462604069A5026959042 @default.
- W2462604069 hasAuthorship W2462604069A5050801327 @default.
- W2462604069 hasAuthorship W2462604069A5069884507 @default.
- W2462604069 hasAuthorship W2462604069A5077612250 @default.
- W2462604069 hasConcept C126322002 @default.
- W2462604069 hasConcept C141071460 @default.
- W2462604069 hasConcept C142724271 @default.
- W2462604069 hasConcept C178853913 @default.
- W2462604069 hasConcept C204787440 @default.
- W2462604069 hasConcept C27081682 @default.
- W2462604069 hasConcept C2776814716 @default.
- W2462604069 hasConcept C2778300832 @default.
- W2462604069 hasConcept C2778399450 @default.
- W2462604069 hasConcept C2778746874 @default.
- W2462604069 hasConcept C2780047204 @default.
- W2462604069 hasConcept C2780580376 @default.
- W2462604069 hasConcept C2780852908 @default.
- W2462604069 hasConcept C2781258859 @default.
- W2462604069 hasConcept C42219234 @default.
- W2462604069 hasConcept C71924100 @default.
- W2462604069 hasConcept C84393581 @default.
- W2462604069 hasConceptScore W2462604069C126322002 @default.
- W2462604069 hasConceptScore W2462604069C141071460 @default.
- W2462604069 hasConceptScore W2462604069C142724271 @default.
- W2462604069 hasConceptScore W2462604069C178853913 @default.
- W2462604069 hasConceptScore W2462604069C204787440 @default.
- W2462604069 hasConceptScore W2462604069C27081682 @default.
- W2462604069 hasConceptScore W2462604069C2776814716 @default.
- W2462604069 hasConceptScore W2462604069C2778300832 @default.
- W2462604069 hasConceptScore W2462604069C2778399450 @default.
- W2462604069 hasConceptScore W2462604069C2778746874 @default.
- W2462604069 hasConceptScore W2462604069C2780047204 @default.
- W2462604069 hasConceptScore W2462604069C2780580376 @default.
- W2462604069 hasConceptScore W2462604069C2780852908 @default.
- W2462604069 hasConceptScore W2462604069C2781258859 @default.
- W2462604069 hasConceptScore W2462604069C42219234 @default.
- W2462604069 hasConceptScore W2462604069C71924100 @default.
- W2462604069 hasConceptScore W2462604069C84393581 @default.
- W2462604069 hasIssue "12" @default.
- W2462604069 hasLocation W24626040691 @default.
- W2462604069 hasOpenAccess W2462604069 @default.
- W2462604069 hasPrimaryLocation W24626040691 @default.
- W2462604069 hasRelatedWork W1516137126 @default.
- W2462604069 hasRelatedWork W1563527633 @default.
- W2462604069 hasRelatedWork W1829448616 @default.
- W2462604069 hasRelatedWork W2023684945 @default.
- W2462604069 hasRelatedWork W2024355782 @default.
- W2462604069 hasRelatedWork W2042983521 @default.
- W2462604069 hasRelatedWork W2068117630 @default.
- W2462604069 hasRelatedWork W2308707991 @default.
- W2462604069 hasRelatedWork W2314025964 @default.
- W2462604069 hasRelatedWork W2328515908 @default.
- W2462604069 hasRelatedWork W2329721840 @default.
- W2462604069 hasRelatedWork W2339830848 @default.
- W2462604069 hasRelatedWork W2491075722 @default.
- W2462604069 hasRelatedWork W2580454443 @default.
- W2462604069 hasRelatedWork W2583822135 @default.
- W2462604069 hasRelatedWork W2619817916 @default.
- W2462604069 hasRelatedWork W2787198540 @default.
- W2462604069 hasRelatedWork W3152872610 @default.
- W2462604069 hasRelatedWork W38821784 @default.
- W2462604069 hasRelatedWork W2945113821 @default.
- W2462604069 hasVolume "5" @default.
- W2462604069 isParatext "false" @default.
- W2462604069 isRetracted "false" @default.
- W2462604069 magId "2462604069" @default.
- W2462604069 workType "article" @default.