Matches in SemOpenAlex for { <https://semopenalex.org/work/W2462633178> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2462633178 abstract "The role of bronchodilator regimens combining a sympathomimetic and a methylxanthine in the treatment of acute exacerbations of asthma remains controversial. This report describes the outcome of 157 emergency room visits for asthma in which patients were randomly assigned to single-drug therapy with intravenous aminophylline, subcutaneous epinephrine, or inhaled isoproterenol or to one of three regimens combining a sympathomimetic and a methylxanthine. The increase in one-second forced expiratory volume after one hour of treatment with the two-drug combinations (0.79 f 0.07 liter) was significantly greater than for epinephrine alone (0.57 f 0.08 liter; p <0.05) but did not differ significantly from that occurring with therapy with isoproterenol alone (0.72 f 0.09 liter; p = NS). This disparity reflects the greater bronchodilation effected by isoproterenol as a single agent than by epinephrine, in the dosing schedules and routes of administration chosen. Among patients presenting with severe airflow obstruction (one-second forced expiratory volume 35 percent or less of normal), the bronchodilator response to isoproterenol alone was 0.88 f 0.14 liter versus 0.51 f 0.11 for epinephrine alone (p <0.05). It is concluded that the observed benefit derived from use of combination therapy depends on the dosage and potency of the particular sympathomimetic to which a methylxanthine is added, and on the severity of the airflow obstruction at presentation." @default.
- W2462633178 created "2016-07-22" @default.
- W2462633178 creator A5020842926 @default.
- W2462633178 creator A5066682597 @default.
- W2462633178 date "1986-01-01" @default.
- W2462633178 modified "2023-09-26" @default.
- W2462633178 title "Is Combination Therapy with Sympathomimetics and Methylxanthines Indicated" @default.
- W2462633178 cites W13573309 @default.
- W2462633178 cites W1578058456 @default.
- W2462633178 cites W1602784471 @default.
- W2462633178 cites W1669289313 @default.
- W2462633178 cites W1911142559 @default.
- W2462633178 cites W1971112869 @default.
- W2462633178 cites W1977039373 @default.
- W2462633178 cites W1988692924 @default.
- W2462633178 cites W1997745000 @default.
- W2462633178 cites W2016921720 @default.
- W2462633178 cites W2038586237 @default.
- W2462633178 cites W2043785722 @default.
- W2462633178 cites W2051158652 @default.
- W2462633178 cites W2053171228 @default.
- W2462633178 cites W2053253649 @default.
- W2462633178 cites W2072065561 @default.
- W2462633178 cites W2091077587 @default.
- W2462633178 cites W2091729755 @default.
- W2462633178 cites W2131375084 @default.
- W2462633178 cites W2168380888 @default.
- W2462633178 cites W2410096923 @default.
- W2462633178 cites W2410121762 @default.
- W2462633178 cites W2413039863 @default.
- W2462633178 cites W35381472 @default.
- W2462633178 hasPublicationYear "1986" @default.
- W2462633178 type Work @default.
- W2462633178 sameAs 2462633178 @default.
- W2462633178 citedByCount "0" @default.
- W2462633178 crossrefType "journal-article" @default.
- W2462633178 hasAuthorship W2462633178A5020842926 @default.
- W2462633178 hasAuthorship W2462633178A5066682597 @default.
- W2462633178 hasConcept C126322002 @default.
- W2462633178 hasConcept C170493617 @default.
- W2462633178 hasConcept C176674119 @default.
- W2462633178 hasConcept C24998067 @default.
- W2462633178 hasConcept C2775859304 @default.
- W2462633178 hasConcept C2776042228 @default.
- W2462633178 hasConcept C2776090920 @default.
- W2462633178 hasConcept C2776202631 @default.
- W2462633178 hasConcept C2776291473 @default.
- W2462633178 hasConcept C2776371117 @default.
- W2462633178 hasConcept C2781018748 @default.
- W2462633178 hasConcept C2908646376 @default.
- W2462633178 hasConcept C2909530129 @default.
- W2462633178 hasConcept C2909548125 @default.
- W2462633178 hasConcept C33789571 @default.
- W2462633178 hasConcept C42219234 @default.
- W2462633178 hasConcept C71924100 @default.
- W2462633178 hasConceptScore W2462633178C126322002 @default.
- W2462633178 hasConceptScore W2462633178C170493617 @default.
- W2462633178 hasConceptScore W2462633178C176674119 @default.
- W2462633178 hasConceptScore W2462633178C24998067 @default.
- W2462633178 hasConceptScore W2462633178C2775859304 @default.
- W2462633178 hasConceptScore W2462633178C2776042228 @default.
- W2462633178 hasConceptScore W2462633178C2776090920 @default.
- W2462633178 hasConceptScore W2462633178C2776202631 @default.
- W2462633178 hasConceptScore W2462633178C2776291473 @default.
- W2462633178 hasConceptScore W2462633178C2776371117 @default.
- W2462633178 hasConceptScore W2462633178C2781018748 @default.
- W2462633178 hasConceptScore W2462633178C2908646376 @default.
- W2462633178 hasConceptScore W2462633178C2909530129 @default.
- W2462633178 hasConceptScore W2462633178C2909548125 @default.
- W2462633178 hasConceptScore W2462633178C33789571 @default.
- W2462633178 hasConceptScore W2462633178C42219234 @default.
- W2462633178 hasConceptScore W2462633178C71924100 @default.
- W2462633178 hasLocation W24626331781 @default.
- W2462633178 hasOpenAccess W2462633178 @default.
- W2462633178 hasPrimaryLocation W24626331781 @default.
- W2462633178 hasRelatedWork W1519406897 @default.
- W2462633178 hasRelatedWork W1885961906 @default.
- W2462633178 hasRelatedWork W1972199104 @default.
- W2462633178 hasRelatedWork W1985554726 @default.
- W2462633178 hasRelatedWork W1990095068 @default.
- W2462633178 hasRelatedWork W2046543152 @default.
- W2462633178 hasRelatedWork W2053171228 @default.
- W2462633178 hasRelatedWork W2053253649 @default.
- W2462633178 hasRelatedWork W2054257100 @default.
- W2462633178 hasRelatedWork W2075616156 @default.
- W2462633178 hasRelatedWork W2084488268 @default.
- W2462633178 hasRelatedWork W2104198435 @default.
- W2462633178 hasRelatedWork W2114059179 @default.
- W2462633178 hasRelatedWork W2129660808 @default.
- W2462633178 hasRelatedWork W2192981600 @default.
- W2462633178 hasRelatedWork W2339726260 @default.
- W2462633178 hasRelatedWork W2395260010 @default.
- W2462633178 hasRelatedWork W2399306229 @default.
- W2462633178 hasRelatedWork W2418046706 @default.
- W2462633178 hasRelatedWork W2602551489 @default.
- W2462633178 isParatext "false" @default.
- W2462633178 isRetracted "false" @default.
- W2462633178 magId "2462633178" @default.
- W2462633178 workType "article" @default.