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- W2462714882 abstract "The ultrastructure of four aldosterone secreting adenomas and of the adjacent zona glomerulosa has been described by the use of stereological techniques. Adenomatous cells (about 2800 microns 3 in volume) invariably displayed a striking abundance of lipid droplets, which occupied about 30% of the cytoplasm. Mitochondria prevalently contained tubulo-lamellar or lamellar cristae, but some cells exhibited organelles with vesicular cristae. Smooth endoplasmic reticulum (SER) was not very abundant. Small lipofuscin-pigment granules were frequently seen and in a few cells they were exceedingly numerous. Zona glomerulosa cells were smaller (about 950 microns 3 in volume) and possessed mitochondria with typical tubulo-lamellar cristae, a plentiful SER and few lipid droplets. They showed the ultrastructural features of elements actively engaged in steroid synthesis. The possible origin of aldosteronoma cells from the zona glomerulosa is discussed." @default.
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- W2462714882 date "1988-07-01" @default.
- W2462714882 modified "2023-09-23" @default.
- W2462714882 title "An ultrastructural stereologic study of aldosterone secreting adrenal adenomas and of adjacent zona glomerulosa." @default.
- W2462714882 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2980230" @default.
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