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- W2462718118 abstract "Introduction: Tobacco use has been widely associated with carcinomas, particularly head, neck and lungs. Tobacco is consumed by various routes via smoking, chewing and inhaling. The anatomical interaction of tobacco body parts accounts for the diversity in causing carcinomas. As lung cancer has been widely implicated as being caused by smoking we believe that use of oral form of tobacco is more associated with carcinomas of head and neck. Methods: This is a retrospective study conducted in the Department of Histopathology of Liaquat National Hospital, Karachi, Pakistan. Cases diagnosed with squamous cell carcinoma of oral region between Dec 2014-Jan 2012 are included. Patients9 case and histopathological records are reviewed and analyzed. Results: These are preliminary results. Between Sep 2014 - Dec 2014 we received 21 specimens. There were n=14 males and n=7 females. History of tobacco use as, chew able in n=15, smoking in n=2 and both forms in n=3 patients. The most common symptom observed was a mouth lump in n=19 patients which involved cheek in n=9, tongue in n=5, lip in n=2 patients. In Patients with history of smokeless tobacco, tumor Grade was found to be well in n=2, n=11 moderate and n=2 poorly differentiated. Lymph node metastasis was found in n=4 patients. In n=2 patients with purely smoking history tumor stage was T2 in both patients, with n=1 having lymph node mets. and both were moderately differentiated. Conclusion: Although preliminary these results indicate that smokeless tobacco causes more harm in the oral region as compared to smoked tobacco in terms of cause, tumor grade and lymph node metastasis. Further studies are warranted in this aspect." @default.
- W2462718118 created "2016-07-22" @default.
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- W2462718118 date "2015-09-01" @default.
- W2462718118 modified "2023-09-26" @default.
- W2462718118 title "Histo-pathological co-relations between smoked and smokeless tobacco in patients with oral cancers in Karachi, Pakistan" @default.
- W2462718118 doi "https://doi.org/10.1183/13993003.congress-2015.pa1881" @default.
- W2462718118 hasPublicationYear "2015" @default.
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