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- W2463272734 abstract "Neuropathic and sympathetically maintained pain often presents diagnostic and therapeutic dilemmas for clinicians; such pain often is resistant to opioids and other conventional analgesics. Chronic pain syndromes that result frequently require multimodal management. The pathophysiologic basis of these types of pain is reviewed briefly. Sympathetically maintained pain is managed largely with sympathetic nerve blocks and rehabilitation. Calcium channel blockers can be useful adjuncts. Drugs that are useful in neuropathic pain including tricyclic antidepressants, anticonvulsants, systemic local anesthetics, and topical capsaicin are described. Other systemic and topical agents that have been used for this indication also are addressed. Several N-methyl-D-aspartate (NMDA) antagonists currently being investigated offer promise of improved neuropathic pain management. The use of antiviral agents to decrease severity of postherpetic neuralgia is described." @default.
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- W2463272734 date "1996-08-01" @default.
- W2463272734 modified "2023-09-27" @default.
- W2463272734 title "Analgesic Drugs for Neuropathic and Sympathetically Maintained Pain" @default.
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- W2463272734 doi "https://doi.org/10.1016/s0749-0690(18)30214-3" @default.
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