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- W2463326712 abstract "ABSTRACT In higher eukaryotes, nuclear envelope (NE) disassembly allows chromatin to condense and spindle microtubules to access kinetochores. The nuclear lamina, which strengthens the NE, is composed of a polymer meshwork made of A- and B-type lamins. We found that the B-type lamin (Lam) is not fully disassembled and continues to localize along the spindle envelope structure during Drosophila male meiosis I, while the A-type lamin (LamC) is completely dispersed throughout the cytoplasm. Among the nuclear pore complex proteins, Nup107 co-localized with Lam during this meiotic division. Surprisingly, Lam depletion resulted in a higher frequency of cytokinesis failure in male meiosis. We also observed the similar meiotic phenotype in Nup107-depleted cells. Abnormal localization of Lam was found in the Nup-depleted cells at premeiotic and meiotic stages. The central spindle microtubules became abnormal and recruitment of a contractile ring component to the cleavage sites was disrupted in Lam-depleted cells and Nup107-depleted cells. Therefore, we speculate that both proteins are required for a reinforcement of the spindle envelope, which supports the formation of central spindle microtubules essential for cytokinesis in Drosophila male meiosis." @default.
- W2463326712 created "2016-07-22" @default.
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- W2463326712 date "2016-07-11" @default.
- W2463326712 modified "2023-10-18" @default.
- W2463326712 title "B-type nuclear lamin and the nuclear pore complex Nup107-160 influences maintenance of the spindle envelope required for cytokinesis in<i>Drosophila</i>male meiosis" @default.
- W2463326712 cites W1482978110 @default.
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- W2463326712 cites W1955474383 @default.
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- W2463326712 cites W1969298304 @default.
- W2463326712 cites W1971934332 @default.
- W2463326712 cites W1978450158 @default.
- W2463326712 cites W1988120993 @default.
- W2463326712 cites W1989927512 @default.
- W2463326712 cites W1996899853 @default.
- W2463326712 cites W1997570561 @default.
- W2463326712 cites W1998733952 @default.
- W2463326712 cites W2001334760 @default.
- W2463326712 cites W2001805380 @default.
- W2463326712 cites W2013576844 @default.
- W2463326712 cites W2016958205 @default.
- W2463326712 cites W2020701957 @default.
- W2463326712 cites W2021957764 @default.
- W2463326712 cites W2027202875 @default.
- W2463326712 cites W2028865319 @default.
- W2463326712 cites W2037289988 @default.
- W2463326712 cites W2037516997 @default.
- W2463326712 cites W2038011290 @default.
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- W2463326712 doi "https://doi.org/10.1242/bio.017566" @default.
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