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- W2463739109 abstract "A phase II evaluation of Vinorelbine is of interest in mediterranean Kaposi's sarcoma (MKS) because of the well-known activity of the natural Vinca alkaloids in this disease. Fifteen patients, both chemonaive and pretreated, were treated with Vinorelbina at the dose level of 17.5 mg/sqm every 2 weeks, 5 times, then 30 mg/sqm every 3 weeks until maximal response (complete regression, or partial regression), followed by 3 consolidation courses. A partial regression was obtained in 9/15 (60) patients, with higher activity in previously untreated patients as compared to pretreated patients. The duration of remission was 6 months in the first group and 2 months in the second one. The median survival (all patients) was 13+ months. Vinorelbine is an active drug in MKS and needs more extensive, evaluation in large, cooperative clinical trials." @default.
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- W2463739109 date "1995-01-01" @default.
- W2463739109 modified "2023-09-22" @default.
- W2463739109 title "Vinorelbine: An active drug in Mediterranean Kaposi's sarcoma" @default.
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