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- W2463990813 abstract "To identify a novel human leukocyte antigen (HLA) B allele and explore its family heritage.A novel HLA allele was suspected upon routine HLA typing using a polymerase chain reaction-sequence specific oligonucleotide probe (PCR-SSOP) assay. The sequence was confirmed with DNA sequencing and compared with its closest matching allele, B*55:02. The family was also investigated.An unusual reaction pattern was detected during routine HLA typing. The sequence was confirmed to be a novel HLA-B allele, which differed from the closest matching allele, B*55:02 in 7 nt positions in exon 2. Among the 7 mutations from 6 codons, there were two amino acids changes including 69Glu→Met and 70Glu→Ala.A novel HLA-B allele has been identified and officially named as B*55:35 by the WHO Nomenclature Committee for Factors of the HLA System (GenBank accession number FJ898284)." @default.
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- W2463990813 date "2013-04-01" @default.
- W2463990813 modified "2023-10-01" @default.
- W2463990813 title "[Identification of a novel HLA allele HLA-B*55:35]." @default.
- W2463990813 doi "https://doi.org/10.3760/cma.j.issn.1003-9406.2013.04.010" @default.
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