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- W2464031427 abstract "Summary:Toinvestigate circadian variation ofcardiac arrhythmias ambulatory electrocardiogram monitoring wascarried outbefore andafter oneweek's treatment with alongacting beta-adrenoceptor blocker, nadolol, in26patients whopresented with symptoms attributable toarrhythmias. Analysis ofthe 24hourprofile ofpremature ventricular contractions showed asignificantly (P<0.05) higher frequency during midday tomidnight thanbetween midnight andmidday. Thefrequency ofsupraventricular tachycardia wassignificantly (P<0.05) higher during theperiods from12.00 hours to16.00 hours (11.0 ±12)and16.00 hours to20.00 hours (11.3 ± 11)thanduring theperiods of00.00 hours to04.00 hours (3.6 ±3)and04.00 hours to08.00 hours (6.0 ±8).Theperiod ofthehighest incidence ofall arrhythmias wasbetween 16.00 hours to24.00 hours, andthat oflowest during theperiod between 04.00 hours to12.00 hours (P< 0.01). After oneweek's treatment with nadolol thefrequency ofall arrhythmias wasstrikingly reduced buttheir pattern ofoccurrence remained unchanged. These studies suggest that patients whopresent with symptoms attributable toarrhythmias tend tohavethese morefrequently during thephysical andmental activities ofthedayandevening presumably duetotheaccompaning sympathetic overactivity." @default.
- W2464031427 created "2016-07-22" @default.
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- W2464031427 date "1986-01-01" @default.
- W2464031427 modified "2023-09-27" @default.
- W2464031427 title "Effect ofalong acting beta-adrenoceptor blocker ondiurnal variation ofcardiac dysrhythmias" @default.
- W2464031427 cites W1996217521 @default.
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- W2464031427 hasPublicationYear "1986" @default.
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