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- W2464082893 abstract "Viral infections are a major health problem, including hepatitis C. An adverse factor comprises serious side effects brought about by conventional therapy. A generally accepted mechanism for drug action involves interference with viral RNA replication. Since physiological effects are often multifaceted, it is reasonable to consider other plausible modes of action. A 1990 article presents a unifying mechanism based on electron transfer-reactive oxygen species-oxidative stress. The present study updates this approach with focus mostly on conjugated imine-iminium ET species. Related ET agents are quinones, aromatic nitro compounds and metal substances." @default.
- W2464082893 created "2016-07-22" @default.
- W2464082893 creator A5076355167 @default.
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- W2464082893 date "2015-01-01" @default.
- W2464082893 modified "2023-09-27" @default.
- W2464082893 title "Unifying Mechanism of Antiviral Drug Action Based on Electron Transfer and Reactive Oxygen Species" @default.
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- W2464082893 doi "https://doi.org/10.1021/bk-2015-1200.ch007" @default.
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