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- W2464271892 abstract "Near-infrared fluorescence (NIRF) endoscopy has a great potential for efficient early detection of dysplastic lesions in the colon. For preclinical studies, we developed a small animal NIRF endoscope and successfully used this device to identify dysplastic lesions in a murine model of chronic colitis. In this chapter, we present a step-by-step protocol for using NIRF endoscopy to examine the location, the size, and the borders of the dysplastic lesions developed in murine colitis. Our studies suggest that NIRF endoscopy is a specific and sensitive technique that provides a unique opportunity to analyze early stages of tumorigenesis in animal models of colon cancer and to perform surveillance colonoscopy in patients with colitis-associated colon cancer." @default.
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- W2464271892 date "2016-01-01" @default.
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- W2464271892 title "Near-Infrared Fluorescence Endoscopy to Detect Dysplastic Lesions in the Mouse Colon" @default.
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- W2464271892 doi "https://doi.org/10.1007/978-1-4939-3603-8_13" @default.
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