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• W2464524241 abstract "We evaluated blood pressure in a sample of patients with neurofibromatosis type 1 (NF1), using ambulatory blood pressure monitoring (ABPM), to deter- mine whether ABPM, when compared with casual BP recordings, allowed the detection of a higher risk for hypertension. We also evaluated the correlation between BP and vascular abnormalities. We studied 69 NF1 patients (36 males and 33 females) with a mean age of 11€4 years, divided into group A, with 24-h mean systolic blood pressure (SBP) or diastolic blood pressure (DBP) 95th percentile. Standard electrocardiography and M- mode, two-dimensional echocardiography were per- formed and all patients were in sinus rhythm. ABPM identified 11 hypertensive patients (16%); 5 had a mean SBP >95th percentile, 3 mean SBPDBP >95th percen- tile, and 3 a mean DBP >95th percentile. Laboratory and other investigations to exclude secondary hypertension were normal. Cardiac abnormalities were found in 13 of the 69 patients (18.8%) with NF1. There were no significant clinical and cardiac differences between the normotensive and hypertensive group. Our data empha- size the importance of periodic ABPM in NF1 patients to diagnose hypertension early and avoid target organ damage and increased mortality." @default.
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• W2464524241 date "2004-01-01" @default.
• W2464524241 modified "2023-09-27" @default.
• W2464524241 title "Blood pressure and cardiovascular involvement in children" @default.
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