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• W2464565604 abstract "In response to voiced speech sounds, auditory-nerve (AN) fibres phase-lock to harmonics near best frequency (BF) and to the fundamental frequency (F0) of voiced sounds. Due to nonlinearities in the healthy ear, phase-locking in each frequency channel is dominated either by a single harmonic, for channels tuned near formants, or by F0, for channels between formants. The alternating dominance of these factors sets up a robust pattern of F0-synchronized rate across best frequency (BF). This profile of a temporally coded measure is transformed into a mean rate profile in the midbrain (inferior colliculus, IC), where neurons are sensitive to low-frequency fluctuations. In the impaired ear, the F0-synchronized rate profile is affected by several factors: Reduced synchrony capture decreases the dominance of a single harmonic near BF on the response. Elevated thresholds also reduce the effect of rate saturation, resulting in increased F0-synchrony. Wider peripheral tuning results in a wider-band envelope with reduced F0 amplitude. In general, sensorineural hearing loss reduces the contrast in AN F0-synchronized rates across BF. Computational models for AN and IC neurons illustrate how hearing loss would affect the F0-synchronized rate profiles set up in response to voiced speech sounds." @default.
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• W2464565604 date "2016-01-01" @default.
• W2464565604 modified "2023-09-27" @default.
• W2464565604 title "Speech Coding in the Midbrain: Effects of Sensorineural Hearing Loss" @default.
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• W2464565604 doi "https://doi.org/10.1007/978-3-319-25474-6_45" @default.
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