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- W2464639360 endingPage "562" @default.
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- W2464639360 abstract "Skeletal muscle mitochondria are highly dynamic and are capable of tremendous expansion to meet cellular energetic demands. Such proliferation in mitochondrial mass requires a synchronized supply of enzymes and structural phospholipids. While transcriptional regulation of mitochondrial enzymes has been extensively studied, there is limited information on how mitochondrial membrane lipids are generated in skeletal muscle. Herein we describe how each class of phospholipids that constitute mitochondrial membranes are synthesized and/or imported, and summarize genetic evidence indicating that membrane phospholipid composition represents a significant modulator of skeletal muscle mitochondrial respiratory function. We also discuss how skeletal muscle mitochondrial phospholipids may mediate the effect of diet and exercise on oxidative metabolism." @default.
- W2464639360 created "2016-07-22" @default.
- W2464639360 creator A5034199210 @default.
- W2464639360 creator A5051699553 @default.
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- W2464639360 date "2016-08-01" @default.
- W2464639360 modified "2023-10-16" @default.
- W2464639360 title "Looking Beyond Structure: Membrane Phospholipids of Skeletal Muscle Mitochondria" @default.
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- W2464639360 doi "https://doi.org/10.1016/j.tem.2016.05.007" @default.
- W2464639360 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4958499" @default.
- W2464639360 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27370525" @default.
- W2464639360 hasPublicationYear "2016" @default.
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