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- W2464757846 abstract "A series of thienocycloheptapyridazines (3aa-dd), structurally related to Minaprine, was synthesized and compounds tested for their affinity towards muscarinic receptors. All of them showed Ki values in the micromolar range towards both the antagonist 3H-QNB and the agonist 3H-OXO-M, thus indicating that they act as antagonists at the muscarinic receptors. Moreover a theoretical study was performed on their interaction behaviour with a three dimensional (3-D) model of the human m1 muscarinic receptor." @default.
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- W2464757846 date "1997-04-01" @default.
- W2464757846 modified "2023-09-23" @default.
- W2464757846 title "Thienocycloheptapyridazines as new muscarinic agents." @default.
- W2464757846 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9197979" @default.
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