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• W2464927114 abstract "Three integrase strand transfer inhibitors (INSTIs), raltegravir (RAL), elvitegravir (EVG) and dolutegravir (DTG), have been approved by the FDA. Resistance against these three INSTIs have been reported and cross-resistance among them has been documented. Due to extensive and dynamic genetic diversity in different HIV-1 variants, significant differences in susceptibility to the INSTIs have been observed among HIV subtypes. This review summarizes what is known about this topic and discusses possible clinical implications." @default.
• W2464927114 created "2016-07-22" @default.
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• W2464927114 date "2016-12-01" @default.
• W2464927114 modified "2023-10-17" @default.
• W2464927114 title "Differences among HIV-1 subtypes in drug resistance against integrase inhibitors" @default.
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• W2464927114 doi "https://doi.org/10.1016/j.meegid.2016.06.047" @default.
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