FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2465001593> ?p ?o ?g. }

• W2465001593 endingPage "91" @default.
• W2465001593 startingPage "71" @default.
• W2465001593 abstract "The global incidence of Candidiasis has risen steadily over the past few decades. Candida species are now among the most common health care –associated pathogens. Most of the studies show that the predominant species C. albicans has been replaced by non albicans Candida with the use of antifungal agents. As various species differ in susceptibility pattern to the newer antifungal agents, antifungal susceptibility test should be performed before administration of antifungal agents. To isolate and identify different Candida species in various clinical specimens, to know the predominant species, to study the risk factors, to compare the advantage of rapid method such as use of Chrom agar over conventional methods for identification and confirmation of Candida species and to detect their antifungal susceptibility pattern. All the clinical samples collected from cases of candidiasis were processed initially using blood agar, MacConkey bile salt lactose agar and SDA with chloramphenicol. Cultures that are identified as candida species were processed using standard yeast identification protocol and chrom agar. Patient detailed clinical history including risk factors was noted. Antifungal susceptibility testing of the yeast isolates was assessed using agar disc diffusion method according to CLSI guidelines. The antifungal drugs used for disc diffusion method are - amphotericin B, Nystatin, fluconazole, Voriconazole, ketaconazole & clotrimazole. A total of 150 Candida isolates were subjected to speciation & antifungal susceptibility testing. Candida isolates were present in 94 (62.6%) males and 56 (37.3%) females. Prolonged use of antibiotics was the major risk factor 41 (27.3%) followed by Biomedical devices 32 (21.3%), Medical causes 21(14%), Diabetes mellitus 17 (11.3%), Trauma 14 (9.3%), Surgical causes 11 (7.3%), Pregnancy 7(4.7%), birth asphyxia 5 (3.3%) and HIV 2 cases (1.3%) respectively. A total of 90 (60%) isolates were obtained from urine, respiratory samples 26 (17.3%), Blood 16 (10.7%), High vaginal swabs 14 (9.3%), wound swabs 4 (2.7%) respectively. In our study Non albicans candida species are more in number over C. albicans. Among Non albicans Candida, C.tropicalis isolation is more, 86 (57.33%). The sensitivity and specificity of CHROM agar was found to be 100% for C.albicans. For C.tropicalis the sensitivity was 100% & specificity was 95.3%. All the isolates of Non albicans Candida were susceptible to Amphotericin B, Nystatin, Voriconazole, Clotrimazole, Itraconazole& Fluconazole. But some species of NAC like C.guilliermondii and C.lipolytica which showed 40% and 33.4% resistance. 22% of strains of C.tropicalis showed resistance against Fluconazole. C.famata showed complete resistance to fluconazole, clotrimazole, Itraconazole, whereas C.dubliniensis & C.guilliermondii showed 33.4% and 40% resistance to Fluconazole. C.albicans showed 100% susceptibility to Amphotericin B & nystatin followed by Ketoconazole (83.3%), Voriconazole (76.6%), Itraconazole (75.8%), Clotrimazole (71.6%) and Fluconazole (63.3%) respectively. Isolation of non – candida albicans species was more than Candida albicans. The predominant species isolated in our study was C .tropicalis. Chrom agar candida medium was found to be useful in identification of candida species. All candida isolates were sensitive to amphotericin & nystatin The antifungal resistance was more in the non albicans species than in Candida albicans. Hence there is a need for speciation, susceptibility testing & periodic surveillance of candida species." @default.
• W2465001593 created "2016-07-22" @default.
• W2465001593 creator A5033019202 @default.
• W2465001593 creator A5036474700 @default.
• W2465001593 creator A5052892988 @default.
• W2465001593 creator A5068879364 @default.
• W2465001593 creator A5084842761 @default.
• W2465001593 date "2016-07-10" @default.
• W2465001593 modified "2023-09-28" @default.
• W2465001593 title "A study of Identification and Antifungal Susceptibility Pattern of Candida species Isolated from Various Clinical Specimens in a Tertiary care Teaching Hospital, Chinakakani, Guntur, Andhra Pradesh, South India" @default.
• W2465001593 cites W1595355479 @default.
• W2465001593 cites W1969514844 @default.
• W2465001593 cites W1974703242 @default.
• W2465001593 cites W1990746885 @default.
• W2465001593 cites W2019207594 @default.
• W2465001593 cites W2041867807 @default.
• W2465001593 cites W2048525926 @default.
• W2465001593 cites W2059666524 @default.
• W2465001593 cites W2065241786 @default.
• W2465001593 cites W2065526216 @default.
• W2465001593 cites W2071912405 @default.
• W2465001593 cites W2082335793 @default.
• W2465001593 cites W2094576454 @default.
• W2465001593 cites W2095696028 @default.
• W2465001593 cites W2108388947 @default.
• W2465001593 cites W2110892287 @default.
• W2465001593 cites W2115093699 @default.
• W2465001593 cites W2127827593 @default.
• W2465001593 cites W2131829756 @default.
• W2465001593 cites W2132236683 @default.
• W2465001593 cites W2133546845 @default.
• W2465001593 cites W2133600906 @default.
• W2465001593 cites W2135303569 @default.
• W2465001593 cites W2137306557 @default.
• W2465001593 cites W2142070590 @default.
• W2465001593 cites W2148691626 @default.
• W2465001593 cites W2149858133 @default.
• W2465001593 cites W2166075607 @default.
• W2465001593 cites W2166190629 @default.
• W2465001593 cites W2166552420 @default.
• W2465001593 cites W2170792133 @default.
• W2465001593 cites W2197167818 @default.
• W2465001593 cites W2271094465 @default.
• W2465001593 cites W2303262578 @default.
• W2465001593 cites W2330232439 @default.
• W2465001593 cites W2339547112 @default.
• W2465001593 cites W2340144328 @default.
• W2465001593 cites W2416949292 @default.
• W2465001593 cites W2998129235 @default.
• W2465001593 cites W418890575 @default.
• W2465001593 cites W1998450785 @default.
• W2465001593 cites W2187823258 @default.
• W2465001593 doi "https://doi.org/10.20546/ijcmas.2016.507.006" @default.
• W2465001593 hasPublicationYear "2016" @default.
• W2465001593 type Work @default.
• W2465001593 sameAs 2465001593 @default.
• W2465001593 citedByCount "7" @default.
• W2465001593 countsByYear W24650015932018 @default.
• W2465001593 countsByYear W24650015932021 @default.
• W2465001593 countsByYear W24650015932022 @default.
• W2465001593 countsByYear W24650015932023 @default.
• W2465001593 crossrefType "journal-article" @default.
• W2465001593 hasAuthorship W2465001593A5033019202 @default.
• W2465001593 hasAuthorship W2465001593A5036474700 @default.
• W2465001593 hasAuthorship W2465001593A5052892988 @default.
• W2465001593 hasAuthorship W2465001593A5068879364 @default.
• W2465001593 hasAuthorship W2465001593A5084842761 @default.
• W2465001593 hasBestOaLocation W24650015931 @default.
• W2465001593 hasConcept C11636898 @default.
• W2465001593 hasConcept C2777328456 @default.
• W2465001593 hasConcept C2777762789 @default.
• W2465001593 hasConcept C2778660310 @default.
• W2465001593 hasConcept C2779443200 @default.
• W2465001593 hasConcept C2779548794 @default.
• W2465001593 hasConcept C2779629538 @default.
• W2465001593 hasConcept C2780104969 @default.
• W2465001593 hasConcept C2780628323 @default.
• W2465001593 hasConcept C2780651595 @default.
• W2465001593 hasConcept C2780690907 @default.
• W2465001593 hasConcept C2780917455 @default.
• W2465001593 hasConcept C523546767 @default.
• W2465001593 hasConcept C54355233 @default.
• W2465001593 hasConcept C86803240 @default.
• W2465001593 hasConcept C89423630 @default.
• W2465001593 hasConceptScore W2465001593C11636898 @default.
• W2465001593 hasConceptScore W2465001593C2777328456 @default.
• W2465001593 hasConceptScore W2465001593C2777762789 @default.
• W2465001593 hasConceptScore W2465001593C2778660310 @default.
• W2465001593 hasConceptScore W2465001593C2779443200 @default.
• W2465001593 hasConceptScore W2465001593C2779548794 @default.
• W2465001593 hasConceptScore W2465001593C2779629538 @default.
• W2465001593 hasConceptScore W2465001593C2780104969 @default.
• W2465001593 hasConceptScore W2465001593C2780628323 @default.
• W2465001593 hasConceptScore W2465001593C2780651595 @default.
• W2465001593 hasConceptScore W2465001593C2780690907 @default.
• W2465001593 hasConceptScore W2465001593C2780917455 @default.
• W2465001593 hasConceptScore W2465001593C523546767 @default.
• W2465001593 hasConceptScore W2465001593C54355233 @default.

• next