FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2465021989> ?p ?o ?g. }

• W2465021989 endingPage "278" @default.
• W2465021989 startingPage "269" @default.
• W2465021989 abstract "This meta-analysis was performed to compare the risks and benefits of combined treatment with tiotropium plus formoterol versus tiotropium alone for stable moderate-to-severe COPD.A comprehensive search of MEDLINE, EMBASE, CINAHL, and the Cochrane Library was performed to identify randomized controlled trials (RCTs) that compared formoterol plus tiotropium to tiotropium alone in COPD patients with a duration of at least 4 weeks. The cut-off date for the search was July 1, 2015. The odds ratio (OR) or mean difference (MD) was used to pool the results with 95% confidence intervals (CI).Eight randomized controlled trials were eligible for this meta-analysis. A significant improvement was observed among patients treated with tiotropium plus formoterol compared with tiotropium alone in the following spirometric indices: mean change in trough FEV1 (P = .02), trough FVC (P = .007), peak FEV1 (P < .00001), and peak FVC (P < .00001). A similar result was noted for the transitional dyspnea index (TDI) (MD 1.46; 95% CI 1.07-1.85) and a clinically significant change in TDI between the tiotropium plus formoterol and tiotropium alone groups (P < .00001). Moreover, a trend toward fewer adverse events was seen in the combination treatment group compared with the tiotropium group (OR .88; 95% CI .70-1.11), although this difference was not statistically significant.Compared with tiotropium alone, tiotropium in combination with formoterol improved lung function and the symptoms of dyspnea in stable moderate-to-severe COPD patients. Moreover, the combined treatment group tended to have fewer adverse events compared with the tiotropium treatment alone group." @default.
• W2465021989 created "2016-07-22" @default.
• W2465021989 creator A5012641833 @default.
• W2465021989 creator A5025357053 @default.
• W2465021989 creator A5036763673 @default.
• W2465021989 creator A5037960195 @default.
• W2465021989 creator A5073022594 @default.
• W2465021989 creator A5077729211 @default.
• W2465021989 creator A5087822489 @default.
• W2465021989 date "2016-08-08" @default.
• W2465021989 modified "2023-10-17" @default.
• W2465021989 title "Tiotropium plus formoterol versus tiotropium alone for stable moderate-to-severe chronic obstructive pulmonary disease: A meta-analysis" @default.
• W2465021989 cites W1980789906 @default.
• W2465021989 cites W1980922801 @default.
• W2465021989 cites W2010355287 @default.
• W2465021989 cites W2048772177 @default.
• W2465021989 cites W2051719749 @default.
• W2465021989 cites W2056765555 @default.
• W2465021989 cites W2072038990 @default.
• W2465021989 cites W2073757316 @default.
• W2465021989 cites W2075195662 @default.
• W2465021989 cites W2085717270 @default.
• W2465021989 cites W2094495786 @default.
• W2465021989 cites W2101932319 @default.
• W2465021989 cites W2127789103 @default.
• W2465021989 cites W2141034778 @default.
• W2465021989 cites W2145005201 @default.
• W2465021989 cites W2150182301 @default.
• W2465021989 cites W2150610623 @default.
• W2465021989 cites W2152040050 @default.
• W2465021989 cites W2158795682 @default.
• W2465021989 cites W2163053179 @default.
• W2465021989 cites W2163267243 @default.
• W2465021989 cites W4211263216 @default.
• W2465021989 cites W4237586956 @default.
• W2465021989 cites W4247387945 @default.
• W2465021989 doi "https://doi.org/10.1111/crj.12526" @default.
• W2465021989 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27402142" @default.
• W2465021989 hasPublicationYear "2016" @default.
• W2465021989 type Work @default.
• W2465021989 sameAs 2465021989 @default.
• W2465021989 citedByCount "3" @default.
• W2465021989 countsByYear W24650219892018 @default.
• W2465021989 countsByYear W24650219892019 @default.
• W2465021989 countsByYear W24650219892021 @default.
• W2465021989 crossrefType "journal-article" @default.
• W2465021989 hasAuthorship W2465021989A5012641833 @default.
• W2465021989 hasAuthorship W2465021989A5025357053 @default.
• W2465021989 hasAuthorship W2465021989A5036763673 @default.
• W2465021989 hasAuthorship W2465021989A5037960195 @default.
• W2465021989 hasAuthorship W2465021989A5073022594 @default.
• W2465021989 hasAuthorship W2465021989A5077729211 @default.
• W2465021989 hasAuthorship W2465021989A5087822489 @default.
• W2465021989 hasConcept C126322002 @default.
• W2465021989 hasConcept C156957248 @default.
• W2465021989 hasConcept C168563851 @default.
• W2465021989 hasConcept C197934379 @default.
• W2465021989 hasConcept C2776042228 @default.
• W2465021989 hasConcept C2776136866 @default.
• W2465021989 hasConcept C2776780178 @default.
• W2465021989 hasConcept C2776968687 @default.
• W2465021989 hasConcept C2777714996 @default.
• W2465021989 hasConcept C2779871671 @default.
• W2465021989 hasConcept C2909086917 @default.
• W2465021989 hasConcept C3018587741 @default.
• W2465021989 hasConcept C42219234 @default.
• W2465021989 hasConcept C71924100 @default.
• W2465021989 hasConceptScore W2465021989C126322002 @default.
• W2465021989 hasConceptScore W2465021989C156957248 @default.
• W2465021989 hasConceptScore W2465021989C168563851 @default.
• W2465021989 hasConceptScore W2465021989C197934379 @default.
• W2465021989 hasConceptScore W2465021989C2776042228 @default.
• W2465021989 hasConceptScore W2465021989C2776136866 @default.
• W2465021989 hasConceptScore W2465021989C2776780178 @default.
• W2465021989 hasConceptScore W2465021989C2776968687 @default.
• W2465021989 hasConceptScore W2465021989C2777714996 @default.
• W2465021989 hasConceptScore W2465021989C2779871671 @default.
• W2465021989 hasConceptScore W2465021989C2909086917 @default.
• W2465021989 hasConceptScore W2465021989C3018587741 @default.
• W2465021989 hasConceptScore W2465021989C42219234 @default.
• W2465021989 hasConceptScore W2465021989C71924100 @default.
• W2465021989 hasIssue "1" @default.
• W2465021989 hasLocation W24650219891 @default.
• W2465021989 hasLocation W24650219892 @default.
• W2465021989 hasOpenAccess W2465021989 @default.
• W2465021989 hasPrimaryLocation W24650219891 @default.
• W2465021989 hasRelatedWork W1194826699 @default.
• W2465021989 hasRelatedWork W1996849150 @default.
• W2465021989 hasRelatedWork W2075094905 @default.
• W2465021989 hasRelatedWork W2094892712 @default.
• W2465021989 hasRelatedWork W2329214458 @default.
• W2465021989 hasRelatedWork W2593451434 @default.
• W2465021989 hasRelatedWork W3109042046 @default.
• W2465021989 hasRelatedWork W330941519 @default.
• W2465021989 hasRelatedWork W4289261525 @default.
• W2465021989 hasRelatedWork W2466610293 @default.
• W2465021989 hasVolume "12" @default.
• W2465021989 isParatext "false" @default.

• next