Matches in SemOpenAlex for { <https://semopenalex.org/work/W2465133022> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2465133022 abstract "Purpose:For intensity modulated radiotherapy, the plan optimization is time consuming with difficulties of selecting objectives and constraints, and their relative weights. A fast and automatic multi-objective optimization algorithm with abilities to predict optimal constraints and manager their trade-offs can help to solve this problem. Our purpose is to develop such a framework and algorithm for a general inverse planning.Methods:There are three main components contained in this proposed multi-objective optimization framework: prediction of initial dosimetric constraints, further adjustment of constraints and plan optimization. We firstly use our previously developed in-house geometry-dosimetry correlation model to predict the optimal patient-specific dosimetric endpoints, and treat them as initial dosimetric constraints. Secondly, we build an endpoint(organ) priority list and a constraint adjustment rule to repeatedly tune these constraints from their initial values, until every single endpoint has no room for further improvement. Lastly, we implement a voxel-independent based FMO algorithm for optimization. During the optimization, a model for tuning these voxel weighting factors respecting to constraints is created. For framework and algorithm evaluation, we randomly selected 20 IMRT prostate cases from the clinic and compared them with our automatic generated plans, in both the efficiency and plan quality.Results:For each evaluated plan, the proposed multi-objective framework could run fluently and automatically. The voxel weighting factor iteration time varied from 10 to 30 under an updated constraint, and the constraint tuning time varied from 20 to 30 for every case until no more stricter constraint is allowed. The average total costing time for the whole optimization procedure is ∼30mins. By comparing the DVHs, better OAR dose sparing could be observed in automatic generated plan, for 13 out of the 20 cases, while others are with competitive results.Conclusion:We have successfully developed a fast and automatic multi-objective optimization for intensity modulated radiotherapy.This work is supported by the National Natural Science Foundation of China (No: 81571771)" @default.
- W2465133022 created "2016-07-22" @default.
- W2465133022 creator A5022599233 @default.
- W2465133022 creator A5051756911 @default.
- W2465133022 creator A5061213901 @default.
- W2465133022 date "2016-06-01" @default.
- W2465133022 modified "2023-09-25" @default.
- W2465133022 title "SU-F-T-342: Dosimetric Constraint Prediction Guided Automatic Mulit-Objective Optimization for Intensity Modulated Radiotherapy" @default.
- W2465133022 doi "https://doi.org/10.1118/1.4956527" @default.
- W2465133022 hasPublicationYear "2016" @default.
- W2465133022 type Work @default.
- W2465133022 sameAs 2465133022 @default.
- W2465133022 citedByCount "0" @default.
- W2465133022 crossrefType "journal-article" @default.
- W2465133022 hasAuthorship W2465133022A5022599233 @default.
- W2465133022 hasAuthorship W2465133022A5051756911 @default.
- W2465133022 hasAuthorship W2465133022A5061213901 @default.
- W2465133022 hasConcept C11413529 @default.
- W2465133022 hasConcept C126255220 @default.
- W2465133022 hasConcept C126838900 @default.
- W2465133022 hasConcept C137836250 @default.
- W2465133022 hasConcept C154945302 @default.
- W2465133022 hasConcept C183115368 @default.
- W2465133022 hasConcept C2524010 @default.
- W2465133022 hasConcept C2776036281 @default.
- W2465133022 hasConcept C2989005 @default.
- W2465133022 hasConcept C33923547 @default.
- W2465133022 hasConcept C41008148 @default.
- W2465133022 hasConcept C54170458 @default.
- W2465133022 hasConcept C55660270 @default.
- W2465133022 hasConcept C71924100 @default.
- W2465133022 hasConcept C75088862 @default.
- W2465133022 hasConceptScore W2465133022C11413529 @default.
- W2465133022 hasConceptScore W2465133022C126255220 @default.
- W2465133022 hasConceptScore W2465133022C126838900 @default.
- W2465133022 hasConceptScore W2465133022C137836250 @default.
- W2465133022 hasConceptScore W2465133022C154945302 @default.
- W2465133022 hasConceptScore W2465133022C183115368 @default.
- W2465133022 hasConceptScore W2465133022C2524010 @default.
- W2465133022 hasConceptScore W2465133022C2776036281 @default.
- W2465133022 hasConceptScore W2465133022C2989005 @default.
- W2465133022 hasConceptScore W2465133022C33923547 @default.
- W2465133022 hasConceptScore W2465133022C41008148 @default.
- W2465133022 hasConceptScore W2465133022C54170458 @default.
- W2465133022 hasConceptScore W2465133022C55660270 @default.
- W2465133022 hasConceptScore W2465133022C71924100 @default.
- W2465133022 hasConceptScore W2465133022C75088862 @default.
- W2465133022 hasLocation W24651330221 @default.
- W2465133022 hasOpenAccess W2465133022 @default.
- W2465133022 hasPrimaryLocation W24651330221 @default.
- W2465133022 hasRelatedWork W1992059679 @default.
- W2465133022 hasRelatedWork W1992073000 @default.
- W2465133022 hasRelatedWork W2019295650 @default.
- W2465133022 hasRelatedWork W2027830872 @default.
- W2465133022 hasRelatedWork W2037897385 @default.
- W2465133022 hasRelatedWork W2047539898 @default.
- W2465133022 hasRelatedWork W2055607777 @default.
- W2465133022 hasRelatedWork W2072049154 @default.
- W2465133022 hasRelatedWork W2073275652 @default.
- W2465133022 hasRelatedWork W2074935286 @default.
- W2465133022 hasRelatedWork W2078588198 @default.
- W2465133022 hasRelatedWork W2084190858 @default.
- W2465133022 hasRelatedWork W2123758638 @default.
- W2465133022 hasRelatedWork W2135238064 @default.
- W2465133022 hasRelatedWork W2148429423 @default.
- W2465133022 hasRelatedWork W2396642458 @default.
- W2465133022 hasRelatedWork W2469349093 @default.
- W2465133022 hasRelatedWork W2889848082 @default.
- W2465133022 hasRelatedWork W2902421371 @default.
- W2465133022 hasRelatedWork W3021761106 @default.
- W2465133022 isParatext "false" @default.
- W2465133022 isRetracted "false" @default.
- W2465133022 magId "2465133022" @default.
- W2465133022 workType "article" @default.