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- W2465203846 abstract "Amyloid fibrils have recently gained a lot of attention due to their morphology, functionality and mechanical strength, allowing for their application in nanofiber-based materials, biosensors, bioactive membranes and tissue engineering scaffolds. The in vitro production of amyloid fibrils is still a slow process, thus hampering the massive production of nanofibers and its consequent use. This work presents a new and faster (2-3h) fibrillation method for hen egg white lysozyme (HEWL) using a deep eutectic solvent based on cholinium chloride and acetic acid. Nanofibers with dimensions of 0.5-1μm in length and 0.02-0.1μm in thickness were obtained. Experimental variables such as temperature and pH were also studied, unveiling their influence in fibrillation time and nanofibers morphology. These results open a new scope for protein fibrillation into nanofibers with applications ranging from medicine to soft matter and nanotechnology." @default.
- W2465203846 created "2016-07-22" @default.
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- W2465203846 creator A5050007630 @default.
- W2465203846 creator A5075089565 @default.
- W2465203846 date "2016-11-01" @default.
- W2465203846 modified "2023-09-24" @default.
- W2465203846 title "Production of lysozyme nanofibers using deep eutectic solvent aqueous solutions" @default.
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- W2465203846 doi "https://doi.org/10.1016/j.colsurfb.2016.07.005" @default.
- W2465203846 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27478961" @default.
- W2465203846 hasPublicationYear "2016" @default.
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