FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2465221076> ?p ?o ?g. }

• W2465221076 abstract "Ulcerative Colitis (UC) is a chronic inflammatory condition that frequently affects men and women of childbearing age. Concerns are often raised by both patients and clinicians regarding the effects of the disease and its treatments on reproduction and lactation. Many studies have examined fertility in UC patients in comparison with the general population. Most of these have not demonstrated a significant difference between the two groups. The observed decrease in fertility in some reports was largely attributable to patient choice, and the use of certain drugs such as sulfasalazine in men. Decreased fertility was also reported in women who have undergone surgery for their disease. Pregnancy is considered high risk in patients with UC. Numerous studies have described the obstetric and neonatal outcomes of these patients, and reported similar pregnancy outcomes in comparison to the general population. However some population-based studies have found an increased incidence of low birth weight and preterm delivery in UC patients. This observed difference seems to be mainly related to disease activity and severity during pregnancy and the appropriate treatment required. On the other hand pregnancy does not appear to increase the risk of disease relapse or severity. The course of UC during pregnancy is partly determined by its activity at conception. Therefore UC patients should be advised to attempt to conceive during periods of disease remission. Patients are often concerned about the safety of UC pharmacotherapy during pregnancy and lactation. Some patients choose to discontinue their maintenance therapy at least until the birth of their baby while others rely on their treating clinician to make the appropriate and safe decision regarding their treatment. Two issues have to be considered in this setting; first is the relative safety of the drug and secondly the benefit risk ratio of its use in pregnancy and lactation. A large amount of safety data is available on drugs that have been in use for decades, however modern medicine has witnessed the introduction of new therapeutic agents that have revolutionized the treatment of inflammatory diseases but there is limited data available regarding their safety during pregnancy and breast feeding. The topic of UC and pregnancy is quite complex involving a range of issues including the effects of both the disease and its treatment options on fertility, pregnancy and lactation, in addition to the effects of pregnancy and lactation on the course of the disease. The aim of this chapter is to review the available data and discuss this topic in more detail." @default.
• W2465221076 created "2016-07-22" @default.
• W2465221076 creator A5051501998 @default.
• W2465221076 creator A5077320760 @default.
• W2465221076 date "2011-11-02" @default.
• W2465221076 modified "2023-09-23" @default.
• W2465221076 title "Ulcerative Colitis and Pregnancy" @default.
• W2465221076 cites W1546907085 @default.
• W2465221076 cites W1558923886 @default.
• W2465221076 cites W1699466167 @default.
• W2465221076 cites W1811605917 @default.
• W2465221076 cites W1955525007 @default.
• W2465221076 cites W1970169983 @default.
• W2465221076 cites W1970764329 @default.
• W2465221076 cites W1976096127 @default.
• W2465221076 cites W1976946457 @default.
• W2465221076 cites W1979276528 @default.
• W2465221076 cites W1988109657 @default.
• W2465221076 cites W1990448536 @default.
• W2465221076 cites W1991631124 @default.
• W2465221076 cites W1991865906 @default.
• W2465221076 cites W2001589398 @default.
• W2465221076 cites W2001598534 @default.
• W2465221076 cites W2003076252 @default.
• W2465221076 cites W2004920081 @default.
• W2465221076 cites W2007082549 @default.
• W2465221076 cites W2013323338 @default.
• W2465221076 cites W2013900807 @default.
• W2465221076 cites W2014665972 @default.
• W2465221076 cites W2020694267 @default.
• W2465221076 cites W2030889094 @default.
• W2465221076 cites W2033750580 @default.
• W2465221076 cites W2034417663 @default.
• W2465221076 cites W2035047655 @default.
• W2465221076 cites W2035525625 @default.
• W2465221076 cites W2035737861 @default.
• W2465221076 cites W203735430 @default.
• W2465221076 cites W2041249493 @default.
• W2465221076 cites W2043329590 @default.
• W2465221076 cites W2046673451 @default.
• W2465221076 cites W2047672705 @default.
• W2465221076 cites W2048046716 @default.
• W2465221076 cites W2048903984 @default.
• W2465221076 cites W2051331012 @default.
• W2465221076 cites W2053880113 @default.
• W2465221076 cites W2054453854 @default.
• W2465221076 cites W2059121897 @default.
• W2465221076 cites W2063459020 @default.
• W2465221076 cites W2064065512 @default.
• W2465221076 cites W2064447790 @default.
• W2465221076 cites W2068990918 @default.
• W2465221076 cites W2073104311 @default.
• W2465221076 cites W2083599883 @default.
• W2465221076 cites W2091039580 @default.
• W2465221076 cites W2092134373 @default.
• W2465221076 cites W2093951536 @default.
• W2465221076 cites W2109094826 @default.
• W2465221076 cites W2112724749 @default.
• W2465221076 cites W2123799332 @default.
• W2465221076 cites W2124937799 @default.
• W2465221076 cites W2132364301 @default.
• W2465221076 cites W2139877652 @default.
• W2465221076 cites W2141890877 @default.
• W2465221076 cites W2159224879 @default.
• W2465221076 cites W2160707036 @default.
• W2465221076 cites W2164889653 @default.
• W2465221076 cites W2170534167 @default.
• W2465221076 cites W2170882954 @default.
• W2465221076 cites W23255181 @default.
• W2465221076 cites W2396660630 @default.
• W2465221076 cites W2401769991 @default.
• W2465221076 cites W2409843888 @default.
• W2465221076 cites W2413732532 @default.
• W2465221076 cites W2414511100 @default.
• W2465221076 cites W2982904857 @default.
• W2465221076 cites W806504602 @default.
• W2465221076 doi "https://doi.org/10.5772/25651" @default.
• W2465221076 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14939904" @default.
• W2465221076 hasPublicationYear "2011" @default.
• W2465221076 type Work @default.
• W2465221076 sameAs 2465221076 @default.
• W2465221076 citedByCount "0" @default.
• W2465221076 crossrefType "book-chapter" @default.
• W2465221076 hasAuthorship W2465221076A5051501998 @default.
• W2465221076 hasAuthorship W2465221076A5077320760 @default.
• W2465221076 hasBestOaLocation W24652210761 @default.
• W2465221076 hasConcept C126322002 @default.
• W2465221076 hasConcept C131872663 @default.
• W2465221076 hasConcept C2779134260 @default.
• W2465221076 hasConcept C2779234561 @default.
• W2465221076 hasConcept C2780479503 @default.
• W2465221076 hasConcept C54355233 @default.
• W2465221076 hasConcept C71924100 @default.
• W2465221076 hasConcept C86803240 @default.
• W2465221076 hasConceptScore W2465221076C126322002 @default.
• W2465221076 hasConceptScore W2465221076C131872663 @default.
• W2465221076 hasConceptScore W2465221076C2779134260 @default.
• W2465221076 hasConceptScore W2465221076C2779234561 @default.
• W2465221076 hasConceptScore W2465221076C2780479503 @default.
• W2465221076 hasConceptScore W2465221076C54355233 @default.

• next