Matches in SemOpenAlex for { <https://semopenalex.org/work/W2465284989> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2465284989 endingPage "650" @default.
- W2465284989 startingPage "649" @default.
- W2465284989 abstract "Stress fibers (SFs) play essential roles in various cellular functions, and they reorganized in response to changes in mechanical environment. Recently, we noticed that the SF networks reappeared following their temporal disruption with cytochalasin D looked similar to those before disruption in rat aortic smooth muscle cells (SMCs). This indicates that the cells may have a memory of SF orientation. The aim of this study was to clarify the mechanism of the memory focusing on the effects of microtubules (MTs) and focal adhesions (FAs) during the reorganization process of SFs. Firstly, we preconditioned the cells with cyclic stretch to make their SFs align in a uniform direction. After cyclic stretching, we depolymerized SFs completely with cytochalasin D, and let them repolymerize in the drug-free medium. To investigate the effects of MTs during the SF repolymerization, we depolymerized MTs. FAs were observed with a surface reflective interference contrast microscopy. In the presence of MTs, repolymerized SFs were randomly orientated with newly formed FAs. In contrast, in the absence of MTs, FAs were not destroyed and the SF alignment was conserved. These indicate that FAs might store the memory of SF alignment while MTs may erase it." @default.
- W2465284989 created "2016-07-22" @default.
- W2465284989 creator A5008982261 @default.
- W2465284989 creator A5017333256 @default.
- W2465284989 creator A5023378285 @default.
- W2465284989 date "2009-01-01" @default.
- W2465284989 modified "2023-09-27" @default.
- W2465284989 title "Intracellular Memory of Stress Fiber Orientation: Focal Adhesions Store It and Microtubules Erase It During Disassembly–Reassembly Process of Stress Fibers" @default.
- W2465284989 doi "https://doi.org/10.1007/978-3-642-03882-2_173" @default.
- W2465284989 hasPublicationYear "2009" @default.
- W2465284989 type Work @default.
- W2465284989 sameAs 2465284989 @default.
- W2465284989 citedByCount "0" @default.
- W2465284989 crossrefType "book-chapter" @default.
- W2465284989 hasAuthorship W2465284989A5008982261 @default.
- W2465284989 hasAuthorship W2465284989A5017333256 @default.
- W2465284989 hasAuthorship W2465284989A5023378285 @default.
- W2465284989 hasConcept C105702510 @default.
- W2465284989 hasConcept C111919701 @default.
- W2465284989 hasConcept C12554922 @default.
- W2465284989 hasConcept C142669718 @default.
- W2465284989 hasConcept C1491633281 @default.
- W2465284989 hasConcept C151166631 @default.
- W2465284989 hasConcept C185592680 @default.
- W2465284989 hasConcept C192562407 @default.
- W2465284989 hasConcept C20418707 @default.
- W2465284989 hasConcept C2776041460 @default.
- W2465284989 hasConcept C2779012151 @default.
- W2465284989 hasConcept C2781099445 @default.
- W2465284989 hasConcept C41008148 @default.
- W2465284989 hasConcept C55493867 @default.
- W2465284989 hasConcept C79879829 @default.
- W2465284989 hasConcept C86803240 @default.
- W2465284989 hasConcept C95444343 @default.
- W2465284989 hasConcept C98045186 @default.
- W2465284989 hasConceptScore W2465284989C105702510 @default.
- W2465284989 hasConceptScore W2465284989C111919701 @default.
- W2465284989 hasConceptScore W2465284989C12554922 @default.
- W2465284989 hasConceptScore W2465284989C142669718 @default.
- W2465284989 hasConceptScore W2465284989C1491633281 @default.
- W2465284989 hasConceptScore W2465284989C151166631 @default.
- W2465284989 hasConceptScore W2465284989C185592680 @default.
- W2465284989 hasConceptScore W2465284989C192562407 @default.
- W2465284989 hasConceptScore W2465284989C20418707 @default.
- W2465284989 hasConceptScore W2465284989C2776041460 @default.
- W2465284989 hasConceptScore W2465284989C2779012151 @default.
- W2465284989 hasConceptScore W2465284989C2781099445 @default.
- W2465284989 hasConceptScore W2465284989C41008148 @default.
- W2465284989 hasConceptScore W2465284989C55493867 @default.
- W2465284989 hasConceptScore W2465284989C79879829 @default.
- W2465284989 hasConceptScore W2465284989C86803240 @default.
- W2465284989 hasConceptScore W2465284989C95444343 @default.
- W2465284989 hasConceptScore W2465284989C98045186 @default.
- W2465284989 hasLocation W24652849891 @default.
- W2465284989 hasOpenAccess W2465284989 @default.
- W2465284989 hasPrimaryLocation W24652849891 @default.
- W2465284989 hasRelatedWork W1968732960 @default.
- W2465284989 hasRelatedWork W1975602559 @default.
- W2465284989 hasRelatedWork W1978908004 @default.
- W2465284989 hasRelatedWork W1979269940 @default.
- W2465284989 hasRelatedWork W1997329904 @default.
- W2465284989 hasRelatedWork W2002502497 @default.
- W2465284989 hasRelatedWork W2005459863 @default.
- W2465284989 hasRelatedWork W2023699847 @default.
- W2465284989 hasRelatedWork W2038854973 @default.
- W2465284989 hasRelatedWork W2057112611 @default.
- W2465284989 hasRelatedWork W2061972505 @default.
- W2465284989 hasRelatedWork W2062204341 @default.
- W2465284989 hasRelatedWork W2087212358 @default.
- W2465284989 hasRelatedWork W2112924183 @default.
- W2465284989 hasRelatedWork W2122283306 @default.
- W2465284989 hasRelatedWork W2127767223 @default.
- W2465284989 hasRelatedWork W2134764403 @default.
- W2465284989 hasRelatedWork W2219307906 @default.
- W2465284989 hasRelatedWork W2808262727 @default.
- W2465284989 hasRelatedWork W2311577107 @default.
- W2465284989 isParatext "false" @default.
- W2465284989 isRetracted "false" @default.
- W2465284989 magId "2465284989" @default.
- W2465284989 workType "book-chapter" @default.