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- W2465366643 endingPage "158" @default.
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- W2465366643 abstract "Living cells can maintain their internal states, react to changing environments, grow, differentiate, divide, etc. All these processes are tightly controlled by what can be called a regulatory program. The logic of the underlying control can sometimes be guessed at by examining the network of influences amongst genetic components. Some associated gene regulatory networks have been studied in prokaryotes and eukaryotes, unveiling various structural features ranging from broad distributions of out-degrees to recurrent motifs, that is small subgraphs having a specific pattern of interactions. To understand what factors may be driving such structuring, a number of groups have introduced frameworks to model the dynamics of gene regulatory networks. In that context, we review here such in silico approaches and show how selection for phenotypes, i.e., network function, can shape network structure." @default.
- W2465366643 created "2016-07-22" @default.
- W2465366643 creator A5005002059 @default.
- W2465366643 creator A5042775184 @default.
- W2465366643 creator A5084525009 @default.
- W2465366643 date "2016-07-01" @default.
- W2465366643 modified "2023-10-18" @default.
- W2465366643 title "Drivers of structural features in gene regulatory networks: From biophysical constraints to biological function" @default.
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