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- W2465497345 abstract "In an open, non-randomized 3-way cross-over study, the bioavailability of 2-oxo-pyrrolidine-1-acetamide (piracetam, Encetrop) from two solid oral formulations and one liquid formulation was tested in 8 healthy male volunteers. The area under the concentration time curve, which is defined to be a measurement for bioequivalence among the three tested galenic formulations correlated very well with the area under the effect intensity-time curve, which was estimated in the same volunteers using electro-physiological methods. The different methods of estimation of bioequivalence show similarity between both solid galenic formulations, while the liquid form exhibits superiority in respect to the oral solid formulations." @default.
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- W2465497345 date "1986-05-01" @default.
- W2465497345 modified "2023-09-27" @default.
- W2465497345 title "[Bioequivalence of piracetam following acute administration of an oral solution or two tablet formulations in volunteers]." @default.
- W2465497345 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3730019" @default.
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